MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY
Aims: To measure the thickness of the peripapillary neurofibrillary layer of the retina (pRNFL) and the volume of the macula in patients with multiple sclerosis (MS), and to compare them with those in healthy volunteers. Study design: prospective pilot study Methods: In this prospective pilot study,...
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| Format: | Article |
| Language: | English |
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Union of Scientists - Stara Zagora
2022-02-01
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| Series: | Science & Research |
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| Online Access: |
http://www.sandtr.org/download.php?id=121
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| _version_ | 1797205569483833344 |
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| author | Vesela Ivancheva Diana Marinova Aleksandar Lyubenov |
| author_facet | Vesela Ivancheva Diana Marinova Aleksandar Lyubenov |
| author_sort | Vesela Ivancheva |
| collection | DOAJ |
| description | Aims: To measure the thickness of the peripapillary neurofibrillary layer of the retina (pRNFL) and the volume of the macula in patients with multiple sclerosis (MS), and to compare them with those in healthy volunteers.
Study design: prospective pilot study
Methods: In this prospective pilot study, a total of 40 eyes were examined: twenty eyes of ten patients with multiple sclerosis and twenty eyes of ten healthy volunteers of the same age without eye or systemic disease. A complete eye examination was performed, including visual acuity with the best correction, refraction, color vision test, and intraocular pressure. Optical coherence tomography (OCT) was performed with 3D Topcon 2000FA + OCT, measuring and comparing the retinal neurofibrillary parameters (pRNFL) and macular volume in all eyes.
Results: OCT studies revealed changes in pRNFL thickness and macular volume in patients with multiple sclerosis.
Conclusion: Patients with MS show thinning of pRNFL and reduction of macular volume - changes that are indicative of the course of neurodegeneration throughout the body. |
| first_indexed | 2024-04-09T20:34:32Z |
| format | Article |
| id | doaj.art-568d02d53edd44f58b7e3249ee591f4b |
| institution | Directory Open Access Journal |
| issn | 2535-0765 |
| language | English |
| last_indexed | 2024-04-24T08:53:12Z |
| publishDate | 2022-02-01 |
| publisher | Union of Scientists - Stara Zagora |
| record_format | Article |
| series | Science & Research |
| spelling | doaj.art-568d02d53edd44f58b7e3249ee591f4b2024-04-16T09:15:37ZengUnion of Scientists - Stara ZagoraScience & Research2535-07652022-02-01121MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHYVesela IvanchevaDiana MarinovaAleksandar LyubenovAims: To measure the thickness of the peripapillary neurofibrillary layer of the retina (pRNFL) and the volume of the macula in patients with multiple sclerosis (MS), and to compare them with those in healthy volunteers. Study design: prospective pilot study Methods: In this prospective pilot study, a total of 40 eyes were examined: twenty eyes of ten patients with multiple sclerosis and twenty eyes of ten healthy volunteers of the same age without eye or systemic disease. A complete eye examination was performed, including visual acuity with the best correction, refraction, color vision test, and intraocular pressure. Optical coherence tomography (OCT) was performed with 3D Topcon 2000FA + OCT, measuring and comparing the retinal neurofibrillary parameters (pRNFL) and macular volume in all eyes. Results: OCT studies revealed changes in pRNFL thickness and macular volume in patients with multiple sclerosis. Conclusion: Patients with MS show thinning of pRNFL and reduction of macular volume - changes that are indicative of the course of neurodegeneration throughout the body. http://www.sandtr.org/download.php?id=121 multiple sclerosisoptical coherence tomographyretina |
| spellingShingle | Vesela Ivancheva Diana Marinova Aleksandar Lyubenov MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY Science & Research multiple sclerosis optical coherence tomography retina |
| title | MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY |
| title_full | MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY |
| title_fullStr | MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY |
| title_full_unstemmed | MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY |
| title_short | MULTIPLE SCLEROSIS: ASSESSMENT OF RETINAL MICROSTRUCTURE BY OPTICAL COHERENCE TOMOGRAPHY |
| title_sort | multiple sclerosis assessment of retinal microstructure by optical coherence tomography |
| topic | multiple sclerosis optical coherence tomography retina |
| url |
http://www.sandtr.org/download.php?id=121
|
| work_keys_str_mv | AT veselaivancheva multiplesclerosisassessmentofretinalmicrostructurebyopticalcoherencetomography AT dianamarinova multiplesclerosisassessmentofretinalmicrostructurebyopticalcoherencetomography AT aleksandarlyubenov multiplesclerosisassessmentofretinalmicrostructurebyopticalcoherencetomography |