Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis
BackgroundThis systematic review and meta-analysis was performed to summarize available evidence of anterior transposition of the ulnar nerve for patients with distal humerus fractures.Materials and MethodsThe databases were searched from PubMed, Cochrane, Embase, Scopus, Web of Science, Chinese Nat...
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| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1005200/full |
| _version_ | 1797959657649602560 |
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| author | Ting Li Ting Li Jingxin Yan Jingxin Yan Qiuyu Ren Qiuyu Ren Jiang Hu Fei Wang Chengwei Xiao Xilin Liu |
| author_facet | Ting Li Ting Li Jingxin Yan Jingxin Yan Qiuyu Ren Qiuyu Ren Jiang Hu Fei Wang Chengwei Xiao Xilin Liu |
| author_sort | Ting Li |
| collection | DOAJ |
| description | BackgroundThis systematic review and meta-analysis was performed to summarize available evidence of anterior transposition of the ulnar nerve for patients with distal humerus fractures.Materials and MethodsThe databases were searched from PubMed, Cochrane, Embase, Scopus, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Chongqing VIP Database (VIP), and Wan Fang Database up to June 2022. The clinical outcome included operation time, fracture healing time, hospital stays, elbow joint function, and ulnar neuritis rate. Statistical analysis was performed with Review Manager 5.3 (Cochrane Collaboration).ResultsA total of 17 studies were included (8 RCTs and 9 retrospective studies), and 1280 patients were analyzed. The results of this meta-analysis showed anterior transposition group had longer operation time (MD = 20.35 min, 95%CI: 12.56–28.14, P < 0.00001). There was no significant difference in fracture healing time (SMD = −0.50, 95%CI: −1.50–0.50, P = 0.33), hospital stays (MD = −1.23 days, 95%CI: −2.72–−0.27, P = 0.11), blood loss (MD = 2.66 ml, 95%CI: −2.45–7.76, P = 0.31), and ulnar neuritis rate (OR = 1.23, 95%CI: 0.63–2.42, P = 0.54) between two groups. Finally, elbow joint motion, elbow joint function, fracture nonunion, and post-operative infection (P > 0.05) between two groups were not significantly statistic difference.ConclusionThis meta-analysis showed that anterior transposition group is not superior to non-transposition group for patients with distal humerus fractures without ulnar nerve injury. On the contrary, non-transposition group have shorter operation time than that of anterior transposition group. Non-transposition group did not increase the post-operative ulnar neuritis rate. Therefore, both anterior transposition group and non- transposition group are the treatment options for patients with distal humerus fractures without ulnar nerve injury. Besides, these findings need to be further verified by multi-center, double-blind, and large sample RCTs. |
| first_indexed | 2024-04-11T00:35:50Z |
| format | Article |
| id | doaj.art-569736b195854cfb8bc85bc9d429eb7a |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T00:35:50Z |
| publishDate | 2023-01-01 |
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| series | Frontiers in Surgery |
| spelling | doaj.art-569736b195854cfb8bc85bc9d429eb7a2023-01-06T18:38:20ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-01-01910.3389/fsurg.2022.10052001005200Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysisTing Li0Ting Li1Jingxin Yan2Jingxin Yan3Qiuyu Ren4Qiuyu Ren5Jiang Hu6Fei Wang7Chengwei Xiao8Xilin Liu9Department of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaDepartment of Postgraduate, Chengdu Medical College, Chengdu, ChinaDepartment of Interventional Therapy, Affiliated Hospital of Qinghai University, Xining, ChinaDepartment of Postgraduate, Qinghai University, Xining, ChinaDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaDepartment of Postgraduate, Chengdu Medical College, Chengdu, ChinaDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaDepartment of Orthopedics, Sichuan Provincial People's Hospital, Chengdu, ChinaBackgroundThis systematic review and meta-analysis was performed to summarize available evidence of anterior transposition of the ulnar nerve for patients with distal humerus fractures.Materials and MethodsThe databases were searched from PubMed, Cochrane, Embase, Scopus, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Chongqing VIP Database (VIP), and Wan Fang Database up to June 2022. The clinical outcome included operation time, fracture healing time, hospital stays, elbow joint function, and ulnar neuritis rate. Statistical analysis was performed with Review Manager 5.3 (Cochrane Collaboration).ResultsA total of 17 studies were included (8 RCTs and 9 retrospective studies), and 1280 patients were analyzed. The results of this meta-analysis showed anterior transposition group had longer operation time (MD = 20.35 min, 95%CI: 12.56–28.14, P < 0.00001). There was no significant difference in fracture healing time (SMD = −0.50, 95%CI: −1.50–0.50, P = 0.33), hospital stays (MD = −1.23 days, 95%CI: −2.72–−0.27, P = 0.11), blood loss (MD = 2.66 ml, 95%CI: −2.45–7.76, P = 0.31), and ulnar neuritis rate (OR = 1.23, 95%CI: 0.63–2.42, P = 0.54) between two groups. Finally, elbow joint motion, elbow joint function, fracture nonunion, and post-operative infection (P > 0.05) between two groups were not significantly statistic difference.ConclusionThis meta-analysis showed that anterior transposition group is not superior to non-transposition group for patients with distal humerus fractures without ulnar nerve injury. On the contrary, non-transposition group have shorter operation time than that of anterior transposition group. Non-transposition group did not increase the post-operative ulnar neuritis rate. Therefore, both anterior transposition group and non- transposition group are the treatment options for patients with distal humerus fractures without ulnar nerve injury. Besides, these findings need to be further verified by multi-center, double-blind, and large sample RCTs.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1005200/fullmeta-analysisanterior transpositionulnar nerve (MeSH)distal humerus fractureseffect |
| spellingShingle | Ting Li Ting Li Jingxin Yan Jingxin Yan Qiuyu Ren Qiuyu Ren Jiang Hu Fei Wang Chengwei Xiao Xilin Liu Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis Frontiers in Surgery meta-analysis anterior transposition ulnar nerve (MeSH) distal humerus fractures effect |
| title | Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis |
| title_full | Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis |
| title_fullStr | Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis |
| title_full_unstemmed | Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis |
| title_short | Efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures: A systematic review and meta-analysis |
| title_sort | efficacy and safety of anterior transposition of the ulnar nerve for distal humerus fractures a systematic review and meta analysis |
| topic | meta-analysis anterior transposition ulnar nerve (MeSH) distal humerus fractures effect |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1005200/full |
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