Autoantibodies targeting interferons and GM-CSF are associated with adverse outcome risk, comorbidities, and pathogen in community-acquired pneumonia

Autoantibodies targeting interferons and GM-CSF are associated with adverse outcome risk, comorbidities, and pathogen in community-acquired pneumonia

IntroductionCytokine autoantibodies (c-aAb) have been associated with pulmonary diseases, including severe novel coronavirus disease 2019 (COVID-19) and pulmonary alveolar proteinosis. This study aimed to determine c-aAb association with community-acquired pneumonia (CAP) etiology (SARS-CoV-2, influ...

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Bibliographic Details
Main Authors: Jakob Hjorth Von Stemann, Arnold Matovu Dungu, Maria Vispe Laguarda, Camilla Koch Ryrsø, Maria Hein Hegelund, Daniel Faurholt-Jepsen, Rikke Krogh-Madsen, Morten Bagge Hansen, Birgitte Lindegaard, Sisse Rye Ostrowski
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
community-acquired pneumonia (CAP)
coronavirus disease 2019
cytokine autoantibody
type 1 interferon
interleukin-10
granulocyte-macrophage colony stimulating factor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1459616/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1459616/full

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