Epidemiological aspects of tuberculosis in HIV infected children
The objective: to assess the methods and time of detection of tuberculosis and HIV infection in children with the co-infection, epidemiological risk factors to develop tuberculosis and effectiveness of preventive measures.Subjects and methods. 75 children in the age from 0 to 14 years old were enrol...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2020-10-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1461 |
| _version_ | 1826563044390469632 |
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| author | E. B. Vasilieva M. E. Lozovskaya L. V. Klochkova Yu. A. Yarovaya O. M. Noskova |
| author_facet | E. B. Vasilieva M. E. Lozovskaya L. V. Klochkova Yu. A. Yarovaya O. M. Noskova |
| author_sort | E. B. Vasilieva |
| collection | DOAJ |
| description | The objective: to assess the methods and time of detection of tuberculosis and HIV infection in children with the co-infection, epidemiological risk factors to develop tuberculosis and effectiveness of preventive measures.Subjects and methods. 75 children in the age from 0 to 14 years old were enrolled in the study. The TB/HIV Group included 25 children with TB/HIV co-infection. The TB Group included 50 HIV negative children with tuberculosis, they made a comparison group.Results: out of 25 children with TB/HIV, only 18 (72%) were aware of perinatal exposure to HIV. HIV infection was confirmed in 11/25 (44%) children during the first months of life, in the remaining 14/25 (56%) it was confirmed later, the latest at 13 years old. In 4 children, HIV infection was detected during examination for tuberculosis. In the TB/HIV Group, in 14/25 (56%) children were exposed to tuberculosis in their families as well as 35/50 (70%) in the TB Group. The positive result of a sputum test of the index case was registered in 7/14 (50%) children of the TB/HIV Group and 19/35 (54.2%) children of the TB Group. Of 25 children of the TB/HIV Group, 17 children (68%) were vaccinated with BCG, and in 9 of them the vaccination was not done properly. |
| first_indexed | 2024-03-12T03:29:48Z |
| format | Article |
| id | doaj.art-569f6cdb6b1745c7b6e6e7e9048f6296 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T09:57:42Z |
| publishDate | 2020-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-569f6cdb6b1745c7b6e6e7e9048f62962025-03-02T11:22:32ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062020-10-01989333710.21292/2075-1230-2020-98-9-33-371459Epidemiological aspects of tuberculosis in HIV infected childrenE. B. Vasilieva0M. E. Lozovskaya1L. V. Klochkova2Yu. A. Yarovaya3O. M. Noskova4St. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversityChildren Infectious Hospital no. 3The objective: to assess the methods and time of detection of tuberculosis and HIV infection in children with the co-infection, epidemiological risk factors to develop tuberculosis and effectiveness of preventive measures.Subjects and methods. 75 children in the age from 0 to 14 years old were enrolled in the study. The TB/HIV Group included 25 children with TB/HIV co-infection. The TB Group included 50 HIV negative children with tuberculosis, they made a comparison group.Results: out of 25 children with TB/HIV, only 18 (72%) were aware of perinatal exposure to HIV. HIV infection was confirmed in 11/25 (44%) children during the first months of life, in the remaining 14/25 (56%) it was confirmed later, the latest at 13 years old. In 4 children, HIV infection was detected during examination for tuberculosis. In the TB/HIV Group, in 14/25 (56%) children were exposed to tuberculosis in their families as well as 35/50 (70%) in the TB Group. The positive result of a sputum test of the index case was registered in 7/14 (50%) children of the TB/HIV Group and 19/35 (54.2%) children of the TB Group. Of 25 children of the TB/HIV Group, 17 children (68%) were vaccinated with BCG, and in 9 of them the vaccination was not done properly.https://www.tibl-journal.com/jour/article/view/1461tuberculosischildrenhiv infectionbcgpreventive treatment |
| spellingShingle | E. B. Vasilieva M. E. Lozovskaya L. V. Klochkova Yu. A. Yarovaya O. M. Noskova Epidemiological aspects of tuberculosis in HIV infected children Туберкулез и болезни лёгких tuberculosis children hiv infection bcg preventive treatment |
| title | Epidemiological aspects of tuberculosis in HIV infected children |
| title_full | Epidemiological aspects of tuberculosis in HIV infected children |
| title_fullStr | Epidemiological aspects of tuberculosis in HIV infected children |
| title_full_unstemmed | Epidemiological aspects of tuberculosis in HIV infected children |
| title_short | Epidemiological aspects of tuberculosis in HIV infected children |
| title_sort | epidemiological aspects of tuberculosis in hiv infected children |
| topic | tuberculosis children hiv infection bcg preventive treatment |
| url | https://www.tibl-journal.com/jour/article/view/1461 |
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