Early echocardiographic alterations in cancer patients during chemotherapy
Aim. To evaluate the early manifestation of cardiotoxicity after the first course of multiagent chemotherapy (MAC) using echocardiography with an assessment of the left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS).Material and methods. The study included 49 cancer patien...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2022-12-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/5093 |
| _version_ | 1826560987487010816 |
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| author | Z. Z.A. Fashafsha P. Sh. Chomakhidze D. F. Mesitskaya A. Yu. Suvorov M. I. Sekacheva E. V. Poddubskaya E. S. Tyukanova M. V. Sankova M. A. Ozova V. D. Levina D. А. Andreev F. Yu. Kopylov |
| author_facet | Z. Z.A. Fashafsha P. Sh. Chomakhidze D. F. Mesitskaya A. Yu. Suvorov M. I. Sekacheva E. V. Poddubskaya E. S. Tyukanova M. V. Sankova M. A. Ozova V. D. Levina D. А. Andreev F. Yu. Kopylov |
| author_sort | Z. Z.A. Fashafsha |
| collection | DOAJ |
| description | Aim. To evaluate the early manifestation of cardiotoxicity after the first course of multiagent chemotherapy (MAC) using echocardiography with an assessment of the left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS).Material and methods. The study included 49 cancer patients with elective MAC.Results. After the first administration of a therapeutic dose of chemotherapy, a decrease in LVEF ≥10 and GLS >15 was demonstrated in more than 6,1% of patients, as well as a subclinical decrease in LVEF ≥5% in 22,4% and a decrease in GLS ≥12% in 24,5%.Conclusion. In cancer patients, after the first course of chemotherapy, GLS dynamics should be assessed during echocardiography as a marker of myocardial dysfunction. |
| first_indexed | 2024-04-09T20:43:16Z |
| format | Article |
| id | doaj.art-569fb9aa9b164e0a8a9d656d51859cca |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:25:01Z |
| publishDate | 2022-12-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-569fb9aa9b164e0a8a9d656d51859cca2025-03-02T11:43:00Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-12-01271110.15829/1560-4071-2022-50933636Early echocardiographic alterations in cancer patients during chemotherapyZ. Z.A. Fashafsha0P. Sh. Chomakhidze1D. F. Mesitskaya2A. Yu. Suvorov3M. I. Sekacheva4E. V. Poddubskaya5E. S. Tyukanova6M. V. Sankova7M. A. Ozova8V. D. Levina9D. А. Andreev10F. Yu. Kopylov11I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityAim. To evaluate the early manifestation of cardiotoxicity after the first course of multiagent chemotherapy (MAC) using echocardiography with an assessment of the left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS).Material and methods. The study included 49 cancer patients with elective MAC.Results. After the first administration of a therapeutic dose of chemotherapy, a decrease in LVEF ≥10 and GLS >15 was demonstrated in more than 6,1% of patients, as well as a subclinical decrease in LVEF ≥5% in 22,4% and a decrease in GLS ≥12% in 24,5%.Conclusion. In cancer patients, after the first course of chemotherapy, GLS dynamics should be assessed during echocardiography as a marker of myocardial dysfunction.https://russjcardiol.elpub.ru/jour/article/view/5093cardiotoxicitymyocardial dysfunctionleft ventricular ejection fractionglobal longitudinal strain |
| spellingShingle | Z. Z.A. Fashafsha P. Sh. Chomakhidze D. F. Mesitskaya A. Yu. Suvorov M. I. Sekacheva E. V. Poddubskaya E. S. Tyukanova M. V. Sankova M. A. Ozova V. D. Levina D. А. Andreev F. Yu. Kopylov Early echocardiographic alterations in cancer patients during chemotherapy Российский кардиологический журнал cardiotoxicity myocardial dysfunction left ventricular ejection fraction global longitudinal strain |
| title | Early echocardiographic alterations in cancer patients during chemotherapy |
| title_full | Early echocardiographic alterations in cancer patients during chemotherapy |
| title_fullStr | Early echocardiographic alterations in cancer patients during chemotherapy |
| title_full_unstemmed | Early echocardiographic alterations in cancer patients during chemotherapy |
| title_short | Early echocardiographic alterations in cancer patients during chemotherapy |
| title_sort | early echocardiographic alterations in cancer patients during chemotherapy |
| topic | cardiotoxicity myocardial dysfunction left ventricular ejection fraction global longitudinal strain |
| url | https://russjcardiol.elpub.ru/jour/article/view/5093 |
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