Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerid...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | Arabic |
Published: |
College of Science for Women, University of Baghdad
2023-06-01
|
Series: | Baghdad Science Journal |
Subjects: | |
Online Access: | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408 |
_version_ | 1797813934067023872 |
---|---|
author | Layla Othman Farhan Baydaa Ahmed Abed AshganSlman Dawood |
author_facet | Layla Othman Farhan Baydaa Ahmed Abed AshganSlman Dawood |
author_sort | Layla Othman Farhan |
collection | DOAJ |
description |
The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM group with respect to the control group, while, no changes were recorded within both diabetic patients groups .The serum insulin level dropped considerably in neuropathy, T2DM group in a comparison with control group. The Adipsin ROC curve showed a clear cut-off value (4510.813, 3967.08) when calculated in neuropathy, T2DM respectively. The study concluded that Adipsin is a diagnostic factor for T2DM with neuropathy
|
first_indexed | 2024-03-13T08:00:02Z |
format | Article |
id | doaj.art-56a20044d82b4cba8f0e1e91c4059e99 |
institution | Directory Open Access Journal |
issn | 2078-8665 2411-7986 |
language | Arabic |
last_indexed | 2024-03-13T08:00:02Z |
publishDate | 2023-06-01 |
publisher | College of Science for Women, University of Baghdad |
record_format | Article |
series | Baghdad Science Journal |
spelling | doaj.art-56a20044d82b4cba8f0e1e91c4059e992023-06-01T19:45:00ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862023-06-0120310.21123/bsj.2022.7408Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and NeuropathyLayla Othman Farhan0Baydaa Ahmed Abed1AshganSlman Dawood2Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq. National Diabetes Center, Mustansiriyah University, Baghdad, Iraq. Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq. The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM group with respect to the control group, while, no changes were recorded within both diabetic patients groups .The serum insulin level dropped considerably in neuropathy, T2DM group in a comparison with control group. The Adipsin ROC curve showed a clear cut-off value (4510.813, 3967.08) when calculated in neuropathy, T2DM respectively. The study concluded that Adipsin is a diagnostic factor for T2DM with neuropathy https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes |
spellingShingle | Layla Othman Farhan Baydaa Ahmed Abed AshganSlman Dawood Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy Baghdad Science Journal Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes |
title | Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy |
title_full | Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy |
title_fullStr | Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy |
title_full_unstemmed | Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy |
title_short | Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy |
title_sort | comparison study between adipsin levels in sera of iraqi patients with diabetes and neuropathy |
topic | Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes |
url | https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408 |
work_keys_str_mv | AT laylaothmanfarhan comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy AT baydaaahmedabed comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy AT ashganslmandawood comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy |