Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy

The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerid...

Full description

Bibliographic Details
Main Authors: Layla Othman Farhan, Baydaa Ahmed Abed, AshganSlman Dawood
Format: Article
Language:Arabic
Published: College of Science for Women, University of Baghdad 2023-06-01
Series:Baghdad Science Journal
Subjects:
Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408
_version_ 1797813934067023872
author Layla Othman Farhan
Baydaa Ahmed Abed
AshganSlman Dawood
author_facet Layla Othman Farhan
Baydaa Ahmed Abed
AshganSlman Dawood
author_sort Layla Othman Farhan
collection DOAJ
description The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total  of ninety  subjects  were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM group with respect to the control group, while,  no changes were recorded within both diabetic patients groups .The serum insulin level dropped considerably  in neuropathy, T2DM group in a comparison with control group. The Adipsin ROC curve showed a clear cut-off value (4510.813, 3967.08) when calculated in neuropathy, T2DM respectively. The study concluded that Adipsin  is a diagnostic factor for T2DM with neuropathy
first_indexed 2024-03-13T08:00:02Z
format Article
id doaj.art-56a20044d82b4cba8f0e1e91c4059e99
institution Directory Open Access Journal
issn 2078-8665
2411-7986
language Arabic
last_indexed 2024-03-13T08:00:02Z
publishDate 2023-06-01
publisher College of Science for Women, University of Baghdad
record_format Article
series Baghdad Science Journal
spelling doaj.art-56a20044d82b4cba8f0e1e91c4059e992023-06-01T19:45:00ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862023-06-0120310.21123/bsj.2022.7408Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and NeuropathyLayla Othman Farhan0Baydaa Ahmed Abed1AshganSlman Dawood2Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq. National Diabetes Center, Mustansiriyah University, Baghdad, Iraq. Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq. The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total  of ninety  subjects  were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM group with respect to the control group, while,  no changes were recorded within both diabetic patients groups .The serum insulin level dropped considerably  in neuropathy, T2DM group in a comparison with control group. The Adipsin ROC curve showed a clear cut-off value (4510.813, 3967.08) when calculated in neuropathy, T2DM respectively. The study concluded that Adipsin  is a diagnostic factor for T2DM with neuropathy https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes
spellingShingle Layla Othman Farhan
Baydaa Ahmed Abed
AshganSlman Dawood
Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
Baghdad Science Journal
Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes
title Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
title_full Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
title_fullStr Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
title_full_unstemmed Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
title_short Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy
title_sort comparison study between adipsin levels in sera of iraqi patients with diabetes and neuropathy
topic Adipsin , Homa IR, Insulin, Neuropathy, Type 2 diabetes
url https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/7408
work_keys_str_mv AT laylaothmanfarhan comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy
AT baydaaahmedabed comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy
AT ashganslmandawood comparisonstudybetweenadipsinlevelsinseraofiraqipatientswithdiabetesandneuropathy