Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

In this study, we have demonstrated the conformational changes to DNA induced by abnormal interactions of copper using circular dichroism, in combination with UV-absorbance and fluorescence spectroscopy. Results confirm that binding of copper to bases of DNA in chromatin is concentration dependent....

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Bibliographic Details
Main Authors:	M. Govindaraju, H.S. Shekar, S.B. Sateesha, P. Vasudeva Raju, K.R. Sambasiva Rao, K.S.J. Rao, A.J. Rajamma
Format:	Article
Language:	English
Published:	Elsevier 2013-10-01
Series:	Journal of Pharmaceutical Analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095177913000300

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