CASPI: collaborative photon processing for active single-photon imaging

Abstract Image sensors capable of capturing individual photons have made tremendous progress in recent years. However, this technology faces a major limitation. Because they capture scene information at the individual photon level, the raw data is sparse and noisy. Here we propose CASPI: Collaborati...

Full description

Bibliographic Details
Main Authors: Jongho Lee, Atul Ingle, Jenu V. Chacko, Kevin W. Eliceiri, Mohit Gupta
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38893-9
_version_ 1827933249400209408
author Jongho Lee
Atul Ingle
Jenu V. Chacko
Kevin W. Eliceiri
Mohit Gupta
author_facet Jongho Lee
Atul Ingle
Jenu V. Chacko
Kevin W. Eliceiri
Mohit Gupta
author_sort Jongho Lee
collection DOAJ
description Abstract Image sensors capable of capturing individual photons have made tremendous progress in recent years. However, this technology faces a major limitation. Because they capture scene information at the individual photon level, the raw data is sparse and noisy. Here we propose CASPI: Collaborative Photon Processing for Active Single-Photon Imaging, a technology-agnostic, application-agnostic, and training-free photon processing pipeline for emerging high-resolution single-photon cameras. By collaboratively exploiting both local and non-local correlations in the spatio-temporal photon data cubes, CASPI estimates scene properties reliably even under very challenging lighting conditions. We demonstrate the versatility of CASPI with two applications: LiDAR imaging over a wide range of photon flux levels, from a sub-photon to high ambient regimes, and live-cell autofluorescence FLIM in low photon count regimes. We envision CASPI as a basic building block of general-purpose photon processing units that will be implemented on-chip in future single-photon cameras.
first_indexed 2024-03-13T07:22:09Z
format Article
id doaj.art-56a5658d04fb4fa1833285f7abfdb9e4
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-03-13T07:22:09Z
publishDate 2023-05-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-56a5658d04fb4fa1833285f7abfdb9e42023-06-04T11:33:55ZengNature PortfolioNature Communications2041-17232023-05-0114111510.1038/s41467-023-38893-9CASPI: collaborative photon processing for active single-photon imagingJongho Lee0Atul Ingle1Jenu V. Chacko2Kevin W. Eliceiri3Mohit Gupta4Department of Computer Sciences, University of Wisconsin-MadisonDepartment of Computer Science, Portland State UniversityLaboratory for Optical and Computational Instrumentation, University of Wisconsin-MadisonLaboratory for Optical and Computational Instrumentation, University of Wisconsin-MadisonDepartment of Computer Sciences, University of Wisconsin-MadisonAbstract Image sensors capable of capturing individual photons have made tremendous progress in recent years. However, this technology faces a major limitation. Because they capture scene information at the individual photon level, the raw data is sparse and noisy. Here we propose CASPI: Collaborative Photon Processing for Active Single-Photon Imaging, a technology-agnostic, application-agnostic, and training-free photon processing pipeline for emerging high-resolution single-photon cameras. By collaboratively exploiting both local and non-local correlations in the spatio-temporal photon data cubes, CASPI estimates scene properties reliably even under very challenging lighting conditions. We demonstrate the versatility of CASPI with two applications: LiDAR imaging over a wide range of photon flux levels, from a sub-photon to high ambient regimes, and live-cell autofluorescence FLIM in low photon count regimes. We envision CASPI as a basic building block of general-purpose photon processing units that will be implemented on-chip in future single-photon cameras.https://doi.org/10.1038/s41467-023-38893-9
spellingShingle Jongho Lee
Atul Ingle
Jenu V. Chacko
Kevin W. Eliceiri
Mohit Gupta
CASPI: collaborative photon processing for active single-photon imaging
Nature Communications
title CASPI: collaborative photon processing for active single-photon imaging
title_full CASPI: collaborative photon processing for active single-photon imaging
title_fullStr CASPI: collaborative photon processing for active single-photon imaging
title_full_unstemmed CASPI: collaborative photon processing for active single-photon imaging
title_short CASPI: collaborative photon processing for active single-photon imaging
title_sort caspi collaborative photon processing for active single photon imaging
url https://doi.org/10.1038/s41467-023-38893-9
work_keys_str_mv AT jongholee caspicollaborativephotonprocessingforactivesinglephotonimaging
AT atulingle caspicollaborativephotonprocessingforactivesinglephotonimaging
AT jenuvchacko caspicollaborativephotonprocessingforactivesinglephotonimaging
AT kevinweliceiri caspicollaborativephotonprocessingforactivesinglephotonimaging
AT mohitgupta caspicollaborativephotonprocessingforactivesinglephotonimaging