Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis

Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis

Candida spp. represent the third most frequent worldwide cause of infection in Intensive Care Units with a mortality rate of almost 40%. The classes of antifungals currently available include azoles, polyenes, echinocandins, pyrimidine derivatives, and allylamines. However, the therapeutical options...

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Bibliographic Details
Main Authors: Marisa Conte, Daniela Eletto, Martina Pannetta, Anna M. Petrone, Maria C. Monti, Chiara Cassiano, Giorgio Giurato, Francesca Rizzo, Peter Tessarz, Antonello Petrella, Alessandra Tosco, Amalia Porta
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Candida
sirtuin
Hst3p deacetylase
H3K56 acetylation
ChIP-seq
antifungals
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1031814/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1031814/full

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