Multipurpose vaginal rings for HIV prevention and non-hormonal contraception
Vaginal rings releasing antiretrovirals - either alone or in combination with contraceptive progestins - are being developed for contraception and prevention of human immunodeficiency virus (HIV) transmission via vagina. However, hormonal contraceptives are associated with numerous side effects and...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University of Huddersfield Press
2022-11-01
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| Series: | British Journal of Pharmacy |
| Subjects: | |
| Online Access: | https://www.bjpharm.org.uk/article/id/1137/ |
| _version_ | 1797825311553880064 |
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| author | Xin Shen Peter Boyd Yahya Dallal Bashi Clare McCoy Karl Malcolm |
| author_facet | Xin Shen Peter Boyd Yahya Dallal Bashi Clare McCoy Karl Malcolm |
| author_sort | Xin Shen |
| collection | DOAJ |
| description | Vaginal rings releasing antiretrovirals - either alone or in combination with contraceptive progestins - are being developed for contraception and prevention of human immunodeficiency virus (HIV) transmission via vagina. However, hormonal contraceptives are associated with numerous side effects and contraindications, and many women are interested in using hormone-free contraceptives. The aim of this project is to develop multipurpose vaginal rings to release copper and/or zinc ions and dapivirine over a month for contraception and HIV prevention. Ring manufacture, swell testing, and in vitro drug release testing have been conducted. The experimental results obtained currently are encouraging and support the continued development of these ring formulations as a novel and interesting multipurpose prevention technology strategy. |
| first_indexed | 2024-03-13T10:52:14Z |
| format | Article |
| id | doaj.art-56ac9cb6558c4196b5fa90e255be7822 |
| institution | Directory Open Access Journal |
| issn | 2058-8356 |
| language | English |
| last_indexed | 2024-03-13T10:52:14Z |
| publishDate | 2022-11-01 |
| publisher | University of Huddersfield Press |
| record_format | Article |
| series | British Journal of Pharmacy |
| spelling | doaj.art-56ac9cb6558c4196b5fa90e255be78222023-05-17T10:54:53ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562022-11-017210.5920/bjpharm.1137Multipurpose vaginal rings for HIV prevention and non-hormonal contraceptionXin Shen0Peter Boyd1Yahya Dallal Bashi2Clare McCoy 3Karl Malcolm4Queen's University of BelfastQueen's University of BelfastQueen's University of BelfastQueen's University of BelfastQueen's University BelfastVaginal rings releasing antiretrovirals - either alone or in combination with contraceptive progestins - are being developed for contraception and prevention of human immunodeficiency virus (HIV) transmission via vagina. However, hormonal contraceptives are associated with numerous side effects and contraindications, and many women are interested in using hormone-free contraceptives. The aim of this project is to develop multipurpose vaginal rings to release copper and/or zinc ions and dapivirine over a month for contraception and HIV prevention. Ring manufacture, swell testing, and in vitro drug release testing have been conducted. The experimental results obtained currently are encouraging and support the continued development of these ring formulations as a novel and interesting multipurpose prevention technology strategy.https://www.bjpharm.org.uk/article/id/1137/multipurpose prevention technologyhivvaginal ringcontraception |
| spellingShingle | Xin Shen Peter Boyd Yahya Dallal Bashi Clare McCoy Karl Malcolm Multipurpose vaginal rings for HIV prevention and non-hormonal contraception British Journal of Pharmacy multipurpose prevention technology hiv vaginal ring contraception |
| title | Multipurpose vaginal rings for HIV prevention and non-hormonal contraception |
| title_full | Multipurpose vaginal rings for HIV prevention and non-hormonal contraception |
| title_fullStr | Multipurpose vaginal rings for HIV prevention and non-hormonal contraception |
| title_full_unstemmed | Multipurpose vaginal rings for HIV prevention and non-hormonal contraception |
| title_short | Multipurpose vaginal rings for HIV prevention and non-hormonal contraception |
| title_sort | multipurpose vaginal rings for hiv prevention and non hormonal contraception |
| topic | multipurpose prevention technology hiv vaginal ring contraception |
| url | https://www.bjpharm.org.uk/article/id/1137/ |
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