Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review
Vaccines are the most promising tools for maintaining public health. Most emerging human infectious diseases are caused by viruses originating from an animal reservoir via zoonotic transmission. Therefore, zoonotic virus spillover and spread in humans have become global health threats. Nanoparticle-...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2023-11-01
|
| Series: | Zoonoses |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0018 |
| _version_ | 1827591960155652096 |
|---|---|
| author | Xiaowei Zhang Zongqiang Cui |
| author_facet | Xiaowei Zhang Zongqiang Cui |
| author_sort | Xiaowei Zhang |
| collection | DOAJ |
| description | Vaccines are the most promising tools for maintaining public health. Most emerging human infectious diseases are caused by viruses originating from an animal reservoir via zoonotic transmission. Therefore, zoonotic virus spillover and spread in humans have become global health threats. Nanoparticle-based vaccines are ideal for antigen delivery, as adjuvants, and as viral structure mimics. Nanoparticles benefit vaccine design and are utilized to protect the antigen cargo, and increase the immunogenicity and efficacy. Therefore, nanoparticle vaccines are a novel method of immunization by which optimal immune responses are elicited. Herein we review current approaches in the development of nanoparticle vaccines and highlight the role of nanoparticle vaccines against zoonotic viral diseases. |
| first_indexed | 2024-03-09T01:40:01Z |
| format | Article |
| id | doaj.art-56ad4510ebe742fcb630f0073379112f |
| institution | Directory Open Access Journal |
| issn | 2737-7466 2737-7474 |
| language | English |
| last_indexed | 2024-03-09T01:40:01Z |
| publishDate | 2023-11-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Zoonoses |
| spelling | doaj.art-56ad4510ebe742fcb630f0073379112f2023-12-08T17:00:24ZengCompuscript LtdZoonoses2737-74662737-74742023-11-013195310.15212/ZOONOSES-2023-0018Nanoparticle-Based Vaccines against Zoonotic Viruses: A ReviewXiaowei ZhangZongqiang CuiVaccines are the most promising tools for maintaining public health. Most emerging human infectious diseases are caused by viruses originating from an animal reservoir via zoonotic transmission. Therefore, zoonotic virus spillover and spread in humans have become global health threats. Nanoparticle-based vaccines are ideal for antigen delivery, as adjuvants, and as viral structure mimics. Nanoparticles benefit vaccine design and are utilized to protect the antigen cargo, and increase the immunogenicity and efficacy. Therefore, nanoparticle vaccines are a novel method of immunization by which optimal immune responses are elicited. Herein we review current approaches in the development of nanoparticle vaccines and highlight the role of nanoparticle vaccines against zoonotic viral diseases.https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0018 |
| spellingShingle | Xiaowei Zhang Zongqiang Cui Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review Zoonoses |
| title | Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review |
| title_full | Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review |
| title_fullStr | Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review |
| title_full_unstemmed | Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review |
| title_short | Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review |
| title_sort | nanoparticle based vaccines against zoonotic viruses a review |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0018 |
| work_keys_str_mv | AT xiaoweizhang nanoparticlebasedvaccinesagainstzoonoticvirusesareview AT zongqiangcui nanoparticlebasedvaccinesagainstzoonoticvirusesareview |