A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells [version 1; referees: 4 approved]
T cell antigen receptors (TCRs) expressed on cytotoxic or helper T cells can only see their specific target antigen as short sequences of peptides bound to the groove of proteins of major histocompatibility complex (MHC) class I, and class II respectively. In addition to the many steps, several part...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-06-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/5-1305/v1 |