The effect of urethral catheterization on the level of prostate-specific antigen

Background: The normal prostate-specific antigen (PSA) level in patients with urethral catheterization is a controversy. We designed this study to investigate the effect of nontraumatic urethral catheterization without urinary retention on serum PSA. Materials and Methods: Seventy patients scheduled...

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Main Authors: Mohammad Hossein Izadpanahi, Hojatollah Salimi, Amir Javid, Salman Eslami
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=38;epage=38;aulast=Izadpanahi
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author Mohammad Hossein Izadpanahi
Hojatollah Salimi
Amir Javid
Salman Eslami
author_facet Mohammad Hossein Izadpanahi
Hojatollah Salimi
Amir Javid
Salman Eslami
author_sort Mohammad Hossein Izadpanahi
collection DOAJ
description Background: The normal prostate-specific antigen (PSA) level in patients with urethral catheterization is a controversy. We designed this study to investigate the effect of nontraumatic urethral catheterization without urinary retention on serum PSA. Materials and Methods: Seventy patients scheduled for urethral catheterization before elective surgeries were randomly selected and included in the study. They were categorized into two age groups: 40–60 years (Group A) and over 60 years (Group B). Total PSA, PSA density, and free/total PSA were assessed before and after catheterization. Results: The PSA levels showed no statistically significant rise after urethral catheterization. The average of PSA level was 1.01 and 1.6 in A and B Groups, respectively, and changed to 1.38 and 1.80 in A and B Groups 1 day after catheterization (P > 0.05). Free/total PSA was 28.75 and 26 in A and B Groups before catheterization and changed to 28.35 and 27.5 in A and B Groups after catheterization (P > 0.05). Conclusion: Nontraumatic urethral catheterization has very little effect on PSA level and in patients with urethral catheter routine evaluation of PSA rising should be considered.
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spelling doaj.art-56aec70a896a448a94bb7092785487862022-12-21T22:46:41ZengWolters Kluwer Medknow PublicationsJournal of Research in Medical Sciences1735-19951735-71362017-01-01221383810.4103/1735-1995.202145The effect of urethral catheterization on the level of prostate-specific antigenMohammad Hossein IzadpanahiHojatollah SalimiAmir JavidSalman EslamiBackground: The normal prostate-specific antigen (PSA) level in patients with urethral catheterization is a controversy. We designed this study to investigate the effect of nontraumatic urethral catheterization without urinary retention on serum PSA. Materials and Methods: Seventy patients scheduled for urethral catheterization before elective surgeries were randomly selected and included in the study. They were categorized into two age groups: 40–60 years (Group A) and over 60 years (Group B). Total PSA, PSA density, and free/total PSA were assessed before and after catheterization. Results: The PSA levels showed no statistically significant rise after urethral catheterization. The average of PSA level was 1.01 and 1.6 in A and B Groups, respectively, and changed to 1.38 and 1.80 in A and B Groups 1 day after catheterization (P > 0.05). Free/total PSA was 28.75 and 26 in A and B Groups before catheterization and changed to 28.35 and 27.5 in A and B Groups after catheterization (P > 0.05). Conclusion: Nontraumatic urethral catheterization has very little effect on PSA level and in patients with urethral catheter routine evaluation of PSA rising should be considered.http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=38;epage=38;aulast=IzadpanahiBiopsyprostate-specific antigenurethral catheterization
spellingShingle Mohammad Hossein Izadpanahi
Hojatollah Salimi
Amir Javid
Salman Eslami
The effect of urethral catheterization on the level of prostate-specific antigen
Journal of Research in Medical Sciences
Biopsy
prostate-specific antigen
urethral catheterization
title The effect of urethral catheterization on the level of prostate-specific antigen
title_full The effect of urethral catheterization on the level of prostate-specific antigen
title_fullStr The effect of urethral catheterization on the level of prostate-specific antigen
title_full_unstemmed The effect of urethral catheterization on the level of prostate-specific antigen
title_short The effect of urethral catheterization on the level of prostate-specific antigen
title_sort effect of urethral catheterization on the level of prostate specific antigen
topic Biopsy
prostate-specific antigen
urethral catheterization
url http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2017;volume=22;issue=1;spage=38;epage=38;aulast=Izadpanahi
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