Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation

Abstract Background Superior Vena Cava (SVC) syndrome, is a quite rare but serious complication after pacemaker lead implantation; most patients are asymptomatic due to the development of adequate venous collateral circulation. Case presentation We report a case of a 75-year-old woman who developed...

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Main Authors: Nicola Mumoli, Antonino Mazzone, Isabella Evangelista, Marco Cei, Alessandra Colombo
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-021-00321-7
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author Nicola Mumoli
Antonino Mazzone
Isabella Evangelista
Marco Cei
Alessandra Colombo
author_facet Nicola Mumoli
Antonino Mazzone
Isabella Evangelista
Marco Cei
Alessandra Colombo
author_sort Nicola Mumoli
collection DOAJ
description Abstract Background Superior Vena Cava (SVC) syndrome, is a quite rare but serious complication after pacemaker lead implantation; most patients are asymptomatic due to the development of adequate venous collateral circulation. Case presentation We report a case of a 75-year-old woman who developed SVC syndrome after transvenous pacemaker implantation with complete resolution of the thrombosis after 3 months of oral anticoagulation. Conclusions Generally other causes as malignancy are considered to be the most common etiology of SVC syndrome, but benign iatrogenic causes, mainly intravascular devices (central vein catheters, cardiac defibrillators and pacemaker wires), are becoming increasingly common. Procedures performed on venous vasculature, causing a possible intimal injury or vein stenosis, provoked by transvenous leads, seem to be the most reasonable explanation for the observed complication.
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spelling doaj.art-56af14c9c6b346ac972095ce852854a82022-12-21T20:37:52ZengBMCThrombosis Journal1477-95602021-11-011911410.1186/s12959-021-00321-7Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulationNicola Mumoli0Antonino Mazzone1Isabella Evangelista2Marco Cei3Alessandra Colombo4Department of Internal Medicine,, Ospedale FornaroliDepartment of Internal Medicine,, Ospedale FornaroliDepartment of Internal Medicine,, Ospedale FornaroliDepartment of Internal Medicine,, Ospedale FornaroliDepartment of Internal Medicine,, Ospedale FornaroliAbstract Background Superior Vena Cava (SVC) syndrome, is a quite rare but serious complication after pacemaker lead implantation; most patients are asymptomatic due to the development of adequate venous collateral circulation. Case presentation We report a case of a 75-year-old woman who developed SVC syndrome after transvenous pacemaker implantation with complete resolution of the thrombosis after 3 months of oral anticoagulation. Conclusions Generally other causes as malignancy are considered to be the most common etiology of SVC syndrome, but benign iatrogenic causes, mainly intravascular devices (central vein catheters, cardiac defibrillators and pacemaker wires), are becoming increasingly common. Procedures performed on venous vasculature, causing a possible intimal injury or vein stenosis, provoked by transvenous leads, seem to be the most reasonable explanation for the observed complication.https://doi.org/10.1186/s12959-021-00321-7Superior vena cavaPacemakerThrombosis
spellingShingle Nicola Mumoli
Antonino Mazzone
Isabella Evangelista
Marco Cei
Alessandra Colombo
Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
Thrombosis Journal
Superior vena cava
Pacemaker
Thrombosis
title Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
title_full Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
title_fullStr Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
title_full_unstemmed Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
title_short Superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
title_sort superior vena cava syndrome after pacemaker implantation treated with direct oral anticoagulation
topic Superior vena cava
Pacemaker
Thrombosis
url https://doi.org/10.1186/s12959-021-00321-7
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