Kluyvera ascorbata infection in Cystic Fibrosis airway disease
Bacilli belonged to genus Kluyvera are Gram negative non-fermentative microorganisms described in the Enterobacteriaceae family, generally considered as saprophytes of the digestive tract.Their role in pathogenesis of infectious disease is unclear, but recently, they are emerged as a cause of clinic...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2011-09-01
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| Series: | Microbiologia Medica |
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| Online Access: | http://www.pagepressjournals.org/index.php/mm/article/view/2357 |
| _version_ | 1811318616354717696 |
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| author | Antonietta Lambiase Vita Dora Iula Valeria Raia Vito Terlizzi Alida Casale Mariassunta Del Pezzo Maria Rosaria Catania Fabio Rossano |
| author_facet | Antonietta Lambiase Vita Dora Iula Valeria Raia Vito Terlizzi Alida Casale Mariassunta Del Pezzo Maria Rosaria Catania Fabio Rossano |
| author_sort | Antonietta Lambiase |
| collection | DOAJ |
| description | Bacilli belonged to genus Kluyvera are Gram negative non-fermentative microorganisms described in the Enterobacteriaceae family, generally considered as saprophytes of the digestive tract.Their role in pathogenesis of infectious disease is unclear, but recently, they are emerged as a cause of clinically significant disease in no-CFpopulation and several anatomic sites are involved as urinary, respiratory and gastrointestinal tracts. In the present note, we describe the identification of Kluyvera ascorbata isolates, obtained from sputum samples of one CF patient (male, 10 years old). The note concerns a patient suffering from chronic obstructive bronchopulmonary disease and chronic Pseudomonas aeruginosa infection. Isolates showed a good growth on MacConkey agar and BCSA, after incubation at 37°C for 24-48 h and they were sensitive to several antibiotics, as cephalosporins, carbapenems, quinolones and trimethoprim-sulfamethoxazole. Clinical observation and the spirometric parameters early before and after isolation of microrganism did not show any worsening status in our patient. The selective pressure given by intensive use of antibiotics in CF patients increases susceptibility to infections by opportunistic microrganisms. Our report underlines the importance of careful bacterial identification and antimicrobial susceptibility study in defining the potential role of new pathogen bacteria in CF lung and to address possible therapeutic strategies that may help to guide antibiotic therapy regimes in CF patients. |
| first_indexed | 2024-04-13T12:27:57Z |
| format | Article |
| id | doaj.art-56b30f90378c4f78965830b397350beb |
| institution | Directory Open Access Journal |
| issn | 2280-6423 |
| language | English |
| last_indexed | 2024-04-13T12:27:57Z |
| publishDate | 2011-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Microbiologia Medica |
| spelling | doaj.art-56b30f90378c4f78965830b397350beb2022-12-22T02:46:57ZengPAGEPress PublicationsMicrobiologia Medica2280-64232011-09-0126310.4081/mm.2011.23571612Kluyvera ascorbata infection in Cystic Fibrosis airway diseaseAntonietta LambiaseVita Dora IulaValeria RaiaVito TerlizziAlida CasaleMariassunta Del PezzoMaria Rosaria CataniaFabio RossanoBacilli belonged to genus Kluyvera are Gram negative non-fermentative microorganisms described in the Enterobacteriaceae family, generally considered as saprophytes of the digestive tract.Their role in pathogenesis of infectious disease is unclear, but recently, they are emerged as a cause of clinically significant disease in no-CFpopulation and several anatomic sites are involved as urinary, respiratory and gastrointestinal tracts. In the present note, we describe the identification of Kluyvera ascorbata isolates, obtained from sputum samples of one CF patient (male, 10 years old). The note concerns a patient suffering from chronic obstructive bronchopulmonary disease and chronic Pseudomonas aeruginosa infection. Isolates showed a good growth on MacConkey agar and BCSA, after incubation at 37°C for 24-48 h and they were sensitive to several antibiotics, as cephalosporins, carbapenems, quinolones and trimethoprim-sulfamethoxazole. Clinical observation and the spirometric parameters early before and after isolation of microrganism did not show any worsening status in our patient. The selective pressure given by intensive use of antibiotics in CF patients increases susceptibility to infections by opportunistic microrganisms. Our report underlines the importance of careful bacterial identification and antimicrobial susceptibility study in defining the potential role of new pathogen bacteria in CF lung and to address possible therapeutic strategies that may help to guide antibiotic therapy regimes in CF patients.http://www.pagepressjournals.org/index.php/mm/article/view/2357Kluyvera ascorbata, Cystic Fibrosis, Chronic obstructive bronchopulmonary disease |
| spellingShingle | Antonietta Lambiase Vita Dora Iula Valeria Raia Vito Terlizzi Alida Casale Mariassunta Del Pezzo Maria Rosaria Catania Fabio Rossano Kluyvera ascorbata infection in Cystic Fibrosis airway disease Microbiologia Medica Kluyvera ascorbata, Cystic Fibrosis, Chronic obstructive bronchopulmonary disease |
| title | Kluyvera ascorbata infection in Cystic Fibrosis airway disease |
| title_full | Kluyvera ascorbata infection in Cystic Fibrosis airway disease |
| title_fullStr | Kluyvera ascorbata infection in Cystic Fibrosis airway disease |
| title_full_unstemmed | Kluyvera ascorbata infection in Cystic Fibrosis airway disease |
| title_short | Kluyvera ascorbata infection in Cystic Fibrosis airway disease |
| title_sort | kluyvera ascorbata infection in cystic fibrosis airway disease |
| topic | Kluyvera ascorbata, Cystic Fibrosis, Chronic obstructive bronchopulmonary disease |
| url | http://www.pagepressjournals.org/index.php/mm/article/view/2357 |
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