Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases
Abstract Background To evaluate the effect of clinicopathologic factors on the prognosis and fertility outcomes of BOT patients. Methods We performed a retrospective analysis of BOT patients who underwent surgical procedures in West China Second University Hospital from 2008 to 2015. The DFS outcome...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12885-020-07262-w |
| _version_ | 1818870781597188096 |
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| author | Na Li Jinhai Gou Lin Li Xiu Ming Ting Wenyi Hu Zhengyu Li |
| author_facet | Na Li Jinhai Gou Lin Li Xiu Ming Ting Wenyi Hu Zhengyu Li |
| author_sort | Na Li |
| collection | DOAJ |
| description | Abstract Background To evaluate the effect of clinicopathologic factors on the prognosis and fertility outcomes of BOT patients. Methods We performed a retrospective analysis of BOT patients who underwent surgical procedures in West China Second University Hospital from 2008 to 2015. The DFS outcomes, potential prognostic factors and fertility outcomes were evaluated. Results Four hundred forty-eight patients were included; 52 recurrences were observed. Ninety-two patients undergoing FSS achieved pregnancy. No significant differences in fertility outcomes were found between the staging and unstaged surgery groups. Staging surgery was not an independent prognostic factor for DFS. Laparoscopy resulted in better prognosis than laparotomy in patients with stage I tumours and a desire for fertility preservation. Conclusion Patients with BOT fail to benefit from surgical staging. Laparoscopy is recommended for patients with stage I disease who desire to preserve fertility. Physicians should pay more attention to risk of recurrence in patients who want to preserve fertility. |
| first_indexed | 2024-12-19T12:12:29Z |
| format | Article |
| id | doaj.art-56b4a2f33afc49489fcd00421fd49aac |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-19T12:12:29Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-56b4a2f33afc49489fcd00421fd49aac2022-12-21T20:22:08ZengBMCBMC Cancer1471-24072020-08-0120111010.1186/s12885-020-07262-wStaging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 casesNa Li0Jinhai Gou1Lin Li2Xiu Ming3Ting Wenyi Hu4Zhengyu Li5Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan UniversityAbstract Background To evaluate the effect of clinicopathologic factors on the prognosis and fertility outcomes of BOT patients. Methods We performed a retrospective analysis of BOT patients who underwent surgical procedures in West China Second University Hospital from 2008 to 2015. The DFS outcomes, potential prognostic factors and fertility outcomes were evaluated. Results Four hundred forty-eight patients were included; 52 recurrences were observed. Ninety-two patients undergoing FSS achieved pregnancy. No significant differences in fertility outcomes were found between the staging and unstaged surgery groups. Staging surgery was not an independent prognostic factor for DFS. Laparoscopy resulted in better prognosis than laparotomy in patients with stage I tumours and a desire for fertility preservation. Conclusion Patients with BOT fail to benefit from surgical staging. Laparoscopy is recommended for patients with stage I disease who desire to preserve fertility. Physicians should pay more attention to risk of recurrence in patients who want to preserve fertility.http://link.springer.com/article/10.1186/s12885-020-07262-wBorderline ovarian tumourSurgery stagingFertility-sparing surgeryDisease-free survival |
| spellingShingle | Na Li Jinhai Gou Lin Li Xiu Ming Ting Wenyi Hu Zhengyu Li Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases BMC Cancer Borderline ovarian tumour Surgery staging Fertility-sparing surgery Disease-free survival |
| title | Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases |
| title_full | Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases |
| title_fullStr | Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases |
| title_full_unstemmed | Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases |
| title_short | Staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility: a retrospective analysis of 448 cases |
| title_sort | staging procedures fail to benefit women with borderline ovarian tumours who want to preserve fertility a retrospective analysis of 448 cases |
| topic | Borderline ovarian tumour Surgery staging Fertility-sparing surgery Disease-free survival |
| url | http://link.springer.com/article/10.1186/s12885-020-07262-w |
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