Integrated Serologic Surveillance of Population Immunity and Disease Transmission
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic sur...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2018-07-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/24/7/17-1928_article |
| _version_ | 1818509536415186944 |
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| author | Benjamin F. Arnold Heather M. Scobie Jeffrey W. Priest Patrick J. Lammie |
| author_facet | Benjamin F. Arnold Heather M. Scobie Jeffrey W. Priest Patrick J. Lammie |
| author_sort | Benjamin F. Arnold |
| collection | DOAJ |
| description | Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex antibody assays would create new opportunities for integrated surveillance. In this perspective, we highlight multiple areas for potential synergy where integrated surveillance could add more value to public health efforts than the current trend of independent disease monitoring through vertical programs. We describe innovations in laboratory and data science that should accelerate integration and identify remaining challenges with respect to specimen collection, testing, and analysis. Throughout, we illustrate how information generated through integrated surveillance platforms can create new opportunities to more quickly and precisely identify global health program gaps that range from undervaccination to emerging pathogens to multilayered health disparities that span diverse communicable diseases. |
| first_indexed | 2024-12-10T22:46:46Z |
| format | Article |
| id | doaj.art-56b6b178690442f6bad870e56e5f9429 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T22:46:46Z |
| publishDate | 2018-07-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-56b6b178690442f6bad870e56e5f94292022-12-22T01:30:32ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-07-012471188119410.3201/eid2407.171928Integrated Serologic Surveillance of Population Immunity and Disease TransmissionBenjamin F. ArnoldHeather M. ScobieJeffrey W. PriestPatrick J. LammieAntibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex antibody assays would create new opportunities for integrated surveillance. In this perspective, we highlight multiple areas for potential synergy where integrated surveillance could add more value to public health efforts than the current trend of independent disease monitoring through vertical programs. We describe innovations in laboratory and data science that should accelerate integration and identify remaining challenges with respect to specimen collection, testing, and analysis. Throughout, we illustrate how information generated through integrated surveillance platforms can create new opportunities to more quickly and precisely identify global health program gaps that range from undervaccination to emerging pathogens to multilayered health disparities that span diverse communicable diseases.https://wwwnc.cdc.gov/eid/article/24/7/17-1928_articleantibodiesimmunologic surveillancecommunicable diseasesemergingvaccinationmalaria |
| spellingShingle | Benjamin F. Arnold Heather M. Scobie Jeffrey W. Priest Patrick J. Lammie Integrated Serologic Surveillance of Population Immunity and Disease Transmission Emerging Infectious Diseases antibodies immunologic surveillance communicable diseases emerging vaccination malaria |
| title | Integrated Serologic Surveillance of Population Immunity and Disease Transmission |
| title_full | Integrated Serologic Surveillance of Population Immunity and Disease Transmission |
| title_fullStr | Integrated Serologic Surveillance of Population Immunity and Disease Transmission |
| title_full_unstemmed | Integrated Serologic Surveillance of Population Immunity and Disease Transmission |
| title_short | Integrated Serologic Surveillance of Population Immunity and Disease Transmission |
| title_sort | integrated serologic surveillance of population immunity and disease transmission |
| topic | antibodies immunologic surveillance communicable diseases emerging vaccination malaria |
| url | https://wwwnc.cdc.gov/eid/article/24/7/17-1928_article |
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