Effects of air pollution exposure on social behavior: a synthesis and call for research
Abstract Background There is a growing literature from both epidemiologic and experimental animal studies suggesting that exposure to air pollution can lead to neurodevelopmental and neuropsychiatric disorders. Here, we suggest that effects of air pollutant exposure on the brain may be even broader,...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-06-01
|
| Series: | Environmental Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12940-021-00761-8 |
| _version_ | 1818723725042778112 |
|---|---|
| author | Chelsea A. Weitekamp Hans A. Hofmann |
| author_facet | Chelsea A. Weitekamp Hans A. Hofmann |
| author_sort | Chelsea A. Weitekamp |
| collection | DOAJ |
| description | Abstract Background There is a growing literature from both epidemiologic and experimental animal studies suggesting that exposure to air pollution can lead to neurodevelopmental and neuropsychiatric disorders. Here, we suggest that effects of air pollutant exposure on the brain may be even broader, with the potential to affect social decision-making in general. Methods We discuss how the neurobiological substrates of social behavior are vulnerable to air pollution, then briefly present studies that examine the effects of air pollutant exposure on social behavior-related outcomes. Results Few experimental studies have investigated the effects of air pollution on social behavior and those that have focus on standard laboratory tests in rodent model systems. Nonetheless, there is sufficient evidence to support a critical need for more research. Conclusion For future research, we suggest a comparative approach that utilizes diverse model systems to probe the effects of air pollution on a wider range of social behaviors, brain regions, and neurochemical pathways. |
| first_indexed | 2024-12-17T21:15:05Z |
| format | Article |
| id | doaj.art-56b6ed9c90c54f97904e260ba71d124d |
| institution | Directory Open Access Journal |
| issn | 1476-069X |
| language | English |
| last_indexed | 2024-12-17T21:15:05Z |
| publishDate | 2021-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Environmental Health |
| spelling | doaj.art-56b6ed9c90c54f97904e260ba71d124d2022-12-21T21:32:22ZengBMCEnvironmental Health1476-069X2021-06-0120111310.1186/s12940-021-00761-8Effects of air pollution exposure on social behavior: a synthesis and call for researchChelsea A. Weitekamp0Hans A. Hofmann1Center for Public Health and Environmental Assessment, U.S. Environmental Protection AgencyDepartment of Integrative Biology, The University of Texas At AustinAbstract Background There is a growing literature from both epidemiologic and experimental animal studies suggesting that exposure to air pollution can lead to neurodevelopmental and neuropsychiatric disorders. Here, we suggest that effects of air pollutant exposure on the brain may be even broader, with the potential to affect social decision-making in general. Methods We discuss how the neurobiological substrates of social behavior are vulnerable to air pollution, then briefly present studies that examine the effects of air pollutant exposure on social behavior-related outcomes. Results Few experimental studies have investigated the effects of air pollution on social behavior and those that have focus on standard laboratory tests in rodent model systems. Nonetheless, there is sufficient evidence to support a critical need for more research. Conclusion For future research, we suggest a comparative approach that utilizes diverse model systems to probe the effects of air pollution on a wider range of social behaviors, brain regions, and neurochemical pathways.https://doi.org/10.1186/s12940-021-00761-8Air pollutionSocial behaviorParticulate matterOzoneSocial decision-making networkDopamine |
| spellingShingle | Chelsea A. Weitekamp Hans A. Hofmann Effects of air pollution exposure on social behavior: a synthesis and call for research Environmental Health Air pollution Social behavior Particulate matter Ozone Social decision-making network Dopamine |
| title | Effects of air pollution exposure on social behavior: a synthesis and call for research |
| title_full | Effects of air pollution exposure on social behavior: a synthesis and call for research |
| title_fullStr | Effects of air pollution exposure on social behavior: a synthesis and call for research |
| title_full_unstemmed | Effects of air pollution exposure on social behavior: a synthesis and call for research |
| title_short | Effects of air pollution exposure on social behavior: a synthesis and call for research |
| title_sort | effects of air pollution exposure on social behavior a synthesis and call for research |
| topic | Air pollution Social behavior Particulate matter Ozone Social decision-making network Dopamine |
| url | https://doi.org/10.1186/s12940-021-00761-8 |
| work_keys_str_mv | AT chelseaaweitekamp effectsofairpollutionexposureonsocialbehaviorasynthesisandcallforresearch AT hansahofmann effectsofairpollutionexposureonsocialbehaviorasynthesisandcallforresearch |