Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement

Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement

This study aimed to enhance the solubility and release characteristics of docetaxel by synthesizing highly porous and stimuli responsive nanosponges, a nano-version of hydrogels with the additional qualities of both hydrogels and nano-systems. Nanosponges were prepared by the free radical polymeriza...

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Bibliographic Details
Main Authors: Syeda Sadia Batool Rizvi, Naveed Akhtar, Muhammad Usman Minhas, Arshad Mahmood, Kifayat Ullah Khan
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Gels
Subjects:
carboxymethyl chitosan (CMC)
β-cyclodextrin
solubility enhancement
nanosponges
docetaxel
cyto-toxicity
Online Access:https://www.mdpi.com/2310-2861/8/1/55

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