The Role of Crosstalk between AR3 and E2F1 in Drug Resistance in Prostate Cancer Cells

The Role of Crosstalk between AR3 and E2F1 in Drug Resistance in Prostate Cancer Cells

Background: Drug resistance is one of the most prevalent causes of death in advanced prostate cancer patients. Combination therapies that target cancer cells via different mechanisms to overcome resistance have gained increased attention in recent years. However, the optimal drug combinations and th...

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Bibliographic Details
Main Authors: Jin Xu, Xi Yang, Dhanraj Deshmukh, Hegang Chen, Shengyun Fang, Yun Qiu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
prostate cancer
combination therapy
drug resistance
androgen receptor splicing variants
E2F1
auranofin
Online Access:https://www.mdpi.com/2073-4409/9/5/1094

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