Malignant peripheral nerve sheath tumor of the breast: case report
<p>Abstract</p> <p>Background</p> <p>Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma of ectomesenchymal origin. It is the malignant counterpart of benign soft tissue tumors like neurofibromas and schwannomas and may often follow them. Common sites...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-12-01
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| Series: | World Journal of Surgical Oncology |
| Online Access: | http://www.wjso.com/content/5/1/142 |
| _version_ | 1811246885392875520 |
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| author | Roy Somak Mandal Shramana Dhingra Kajal Khurana Nita |
| author_facet | Roy Somak Mandal Shramana Dhingra Kajal Khurana Nita |
| author_sort | Roy Somak |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma of ectomesenchymal origin. It is the malignant counterpart of benign soft tissue tumors like neurofibromas and schwannomas and may often follow them. Common sites include deeper soft tissues, usually in the proximity of a nerve trunk. Breast is an extremely rare location of this lesion and presentation as a breast lump in the absence of pain or previous benign neural tumor is even rarer.</p> <p>Case presentation</p> <p>A 38-year-old female presented with complaints of painless, hard breast lump for three months which was clinically suspected to be a ductal carcinoma with inconclusive fine needle aspiration cytology. Histopathology revealed a malignant spindle cell tumor which was confirmed to be malignant peripheral nerve sheath tumor on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.</p> <p>Conclusion</p> <p>To the best of our knowledge only six such case reports have been published in literature. The differential diagnosis of malignant peripheral nerve sheath tumor should be considered by the clinician as well as the pathologists in the work-up of a breast neoplasm as treatment and prognosis of this rare malignancy is different.</p> |
| first_indexed | 2024-04-12T15:00:53Z |
| format | Article |
| id | doaj.art-56b9071838dd4585829f80e1d0e41f43 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-12T15:00:53Z |
| publishDate | 2007-12-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-56b9071838dd4585829f80e1d0e41f432022-12-22T03:28:05ZengBMCWorld Journal of Surgical Oncology1477-78192007-12-015114210.1186/1477-7819-5-142Malignant peripheral nerve sheath tumor of the breast: case reportRoy SomakMandal ShramanaDhingra KajalKhurana Nita<p>Abstract</p> <p>Background</p> <p>Malignant peripheral nerve sheath tumor is a rare soft tissue sarcoma of ectomesenchymal origin. It is the malignant counterpart of benign soft tissue tumors like neurofibromas and schwannomas and may often follow them. Common sites include deeper soft tissues, usually in the proximity of a nerve trunk. Breast is an extremely rare location of this lesion and presentation as a breast lump in the absence of pain or previous benign neural tumor is even rarer.</p> <p>Case presentation</p> <p>A 38-year-old female presented with complaints of painless, hard breast lump for three months which was clinically suspected to be a ductal carcinoma with inconclusive fine needle aspiration cytology. Histopathology revealed a malignant spindle cell tumor which was confirmed to be malignant peripheral nerve sheath tumor on the basis of immunopositivity for vimentin, neurone specific enolase and S-100.</p> <p>Conclusion</p> <p>To the best of our knowledge only six such case reports have been published in literature. The differential diagnosis of malignant peripheral nerve sheath tumor should be considered by the clinician as well as the pathologists in the work-up of a breast neoplasm as treatment and prognosis of this rare malignancy is different.</p>http://www.wjso.com/content/5/1/142 |
| spellingShingle | Roy Somak Mandal Shramana Dhingra Kajal Khurana Nita Malignant peripheral nerve sheath tumor of the breast: case report World Journal of Surgical Oncology |
| title | Malignant peripheral nerve sheath tumor of the breast: case report |
| title_full | Malignant peripheral nerve sheath tumor of the breast: case report |
| title_fullStr | Malignant peripheral nerve sheath tumor of the breast: case report |
| title_full_unstemmed | Malignant peripheral nerve sheath tumor of the breast: case report |
| title_short | Malignant peripheral nerve sheath tumor of the breast: case report |
| title_sort | malignant peripheral nerve sheath tumor of the breast case report |
| url | http://www.wjso.com/content/5/1/142 |
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