Vanillic Acid Ameliorates Demyelination in a Cuprizone-Induced Multiple Sclerosis Rat Model: Possible Underlying Mechanisms

Vanillic Acid Ameliorates Demyelination in a Cuprizone-Induced Multiple Sclerosis Rat Model: Possible Underlying Mechanisms

Objective: To investigate the effect of vanillic acid (VA) on a Cuprizone (Cup) demyelinating rat model and the mechanisms behind such effect. Methods: Thirty adult male Sprague Dawley (SD) rats were randomly divided into three groups: control, Cuprizone, and VA groups. Cuprizone was administrated a...

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Bibliographic Details
Main Authors: Sally M. Safwat, Mahmoud El Tohamy, Moutasem Salih Aboonq, Amaal Alrehaili, Ahmad A. Assinnari, Abdulrahman S. Bahashwan, Ahmed A. ElGendy, Abdelaziz M. Hussein
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Brain Sciences
Subjects:
cuprizone
demyelinating
vanillic acid
Nrf2
neuroinflammation
Online Access:https://www.mdpi.com/2076-3425/14/1/12

Internet

https://www.mdpi.com/2076-3425/14/1/12

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