Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection

Abstract Aim The aim of this study is to evaluate the functional outcomes and complications after non-fusion knee arthrodesis with a modular segmental intramedullary implant used for infected total knee arthroplasty revisions. Methods A retrospective review of the patients who had been surgically tr...

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Main Authors: Kadir Büyükdoğan, Yusuf Öztürkmen, Barlas Goker, Melih Oral, Tolga Atay, Korhan Özkan, Ömür Çağlar, Mehmet Ayvaz
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-023-07016-2
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author Kadir Büyükdoğan
Yusuf Öztürkmen
Barlas Goker
Melih Oral
Tolga Atay
Korhan Özkan
Ömür Çağlar
Mehmet Ayvaz
author_facet Kadir Büyükdoğan
Yusuf Öztürkmen
Barlas Goker
Melih Oral
Tolga Atay
Korhan Özkan
Ömür Çağlar
Mehmet Ayvaz
author_sort Kadir Büyükdoğan
collection DOAJ
description Abstract Aim The aim of this study is to evaluate the functional outcomes and complications after non-fusion knee arthrodesis with a modular segmental intramedullary implant used for infected total knee arthroplasty revisions. Methods A retrospective review of the patients who had been surgically treated with a modular intramedullary arthrodesis implant for recurrent infection after revision TKA between January 2016 and February 2020 were included. The indications for arthrodesis were failed infected TKA with massive bone loss, deficient extensor mechanism and poor soft tissue coverage that precluded joint reconstruction with revision TKA implants. Clinical outcomes were assesed with visual analogue scale for pain (pVAS), Oxford knee score (OKS) and 12-item short form survey (SF-12). Full-length radiographs were used to verify limb length discrepancies (LLD). Results Fourteen patients (4 male and 10 female) patients with a mean age of 69.3 (range, 59 to 81) years at time of surgery were available for final follow-up at a mean of 28.8 months (range, 24–35 months). All clinical outcome scores improved at the final follow-up (pVAS, 8.5 to 2.6, p = .01; OKS, 12.6 to 33.8, p = .02; SF-12 physical, 22.9 to 32.1, p = .01 and SF-12 mental, 27.7 to 40.2, p = .01). The mean LLD was 1.0 cm (range, + 15 – 2.3 cm). Re-infection was detected in three patients (21.4%). Two patients were managed with suppressive antibiotic treatment and a third patient required repeat 2-stage revision procedure. In one patient, a periprosthetic femur fracture was observed and treated with plate osteosynthesis. Conclusion Uncontrolled infection after total knee arthroplasty can be effectively treated with arthrodesis using a modular intramedullary nail and satisfactory functional results can be obtained. Level of evidence Level 4, Retrospective cohort study.
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spelling doaj.art-56bd1964d9554233bb497e431a90e2022023-11-19T12:08:44ZengBMCBMC Musculoskeletal Disorders1471-24742023-11-012411910.1186/s12891-023-07016-2Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infectionKadir Büyükdoğan0Yusuf Öztürkmen1Barlas Goker2Melih Oral3Tolga Atay4Korhan Özkan5Ömür Çağlar6Mehmet Ayvaz7Department of Orthopedic Surgery, Güven HospitalDepartment of Orthopedics and Traumatology, Istanbul Training and Research HospitalDepartment of Orthopedics and Traumatology, Faculty of Medicine, Hacettepe UniversityDepartment of Orthopedics and Traumatology, Faculty of Medicine, Hacettepe UniversityDepartment of Orthopedics and Traumatology, Faculty of Medicine, Suleyman Demirel UniversityOrthopedics and Traumatology Department, Faculty of Medicine, Medeniyet UniversityDepartment of Orthopedics and Traumatology, Faculty of Medicine, Hacettepe UniversityDepartment of Orthopedics and Traumatology, Faculty of Medicine, Hacettepe UniversityAbstract Aim The aim of this study is to evaluate the functional outcomes and complications after non-fusion knee arthrodesis with a modular segmental intramedullary implant used for infected total knee arthroplasty revisions. Methods A retrospective review of the patients who had been surgically treated with a modular intramedullary arthrodesis implant for recurrent infection after revision TKA between January 2016 and February 2020 were included. The indications for arthrodesis were failed infected TKA with massive bone loss, deficient extensor mechanism and poor soft tissue coverage that precluded joint reconstruction with revision TKA implants. Clinical outcomes were assesed with visual analogue scale for pain (pVAS), Oxford knee score (OKS) and 12-item short form survey (SF-12). Full-length radiographs were used to verify limb length discrepancies (LLD). Results Fourteen patients (4 male and 10 female) patients with a mean age of 69.3 (range, 59 to 81) years at time of surgery were available for final follow-up at a mean of 28.8 months (range, 24–35 months). All clinical outcome scores improved at the final follow-up (pVAS, 8.5 to 2.6, p = .01; OKS, 12.6 to 33.8, p = .02; SF-12 physical, 22.9 to 32.1, p = .01 and SF-12 mental, 27.7 to 40.2, p = .01). The mean LLD was 1.0 cm (range, + 15 – 2.3 cm). Re-infection was detected in three patients (21.4%). Two patients were managed with suppressive antibiotic treatment and a third patient required repeat 2-stage revision procedure. In one patient, a periprosthetic femur fracture was observed and treated with plate osteosynthesis. Conclusion Uncontrolled infection after total knee arthroplasty can be effectively treated with arthrodesis using a modular intramedullary nail and satisfactory functional results can be obtained. Level of evidence Level 4, Retrospective cohort study.https://doi.org/10.1186/s12891-023-07016-2Knee ArthrodesisTotal knee arthroplastyPeriprosthetic joint infectionModular intramedullary nail
spellingShingle Kadir Büyükdoğan
Yusuf Öztürkmen
Barlas Goker
Melih Oral
Tolga Atay
Korhan Özkan
Ömür Çağlar
Mehmet Ayvaz
Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
BMC Musculoskeletal Disorders
Knee Arthrodesis
Total knee arthroplasty
Periprosthetic joint infection
Modular intramedullary nail
title Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
title_full Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
title_fullStr Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
title_full_unstemmed Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
title_short Early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
title_sort early results of a novel modular knee arthrodesis implant after uncontrolled periprosthetic knee joint infection
topic Knee Arthrodesis
Total knee arthroplasty
Periprosthetic joint infection
Modular intramedullary nail
url https://doi.org/10.1186/s12891-023-07016-2
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