Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens

Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens

Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is controlled by vaccine policy in many countries. For vaccine potency, the content of intact virus particles (146S antigens) is critical, and the sucrose density gradient (SDG) fractionation is the gold standard for the quantification of...

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Bibliographic Details
Main Authors: Ah-Young Kim, Sun Young Park, Sang Hyun Park, Jong Sook Jin, Eun-Sol Kim, Jae Young Kim, Jong-Hyeon Park, Young-Joon Ko
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Vaccines
Subjects:
foot-and-mouth disease (FMD)
pretreatment
quantification
vaccine antigen
SE-HPLC
Online Access:https://www.mdpi.com/2076-393X/9/11/1361

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