INFLUENCE OF HYPOXIA INDUCIBLE FACTOR ALPHA (HIF-1α) ON CELLULAR VIABILITY OF LONG-TERM CRYOPRESERVED PERIPHERAL BLOOD STEM CELLS

Objective: Hypoxia Inducible Factor alpha (HIF-1α) has been described as an important regulator of cellular oxygen homeostasis. The activation of the HIF-1α transcription factor in response to reduced oxygen availability is an important mechanism used by cells under hypoxic conditions that ensures t...

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Bibliographic Details
Main Authors: AF Callera, ES Rosa, F Callera
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137923011501