Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus
The experiment was conducted to clarify sumithion induced hematoxicity in silver barb (Barbonymus gonionotus) through in vivo exposures (25 % and 50 % of LC50 of sumithion) and subsequent recovery patterns using normal and probiotic treated feed were also assessed. Three treatments each incorporatin...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
|
| Series: | Toxicology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221475002200018X |
| _version_ | 1811178794931716096 |
|---|---|
| author | Kamrunnaher Kole Md. Rabiul Islam Cynthia Elisia Mrong Nusrat Nahid Neepa Nargis Sultana Md. Rezwanul Haque Sadia Salam Golam Mohammod Mostakim |
| author_facet | Kamrunnaher Kole Md. Rabiul Islam Cynthia Elisia Mrong Nusrat Nahid Neepa Nargis Sultana Md. Rezwanul Haque Sadia Salam Golam Mohammod Mostakim |
| author_sort | Kamrunnaher Kole |
| collection | DOAJ |
| description | The experiment was conducted to clarify sumithion induced hematoxicity in silver barb (Barbonymus gonionotus) through in vivo exposures (25 % and 50 % of LC50 of sumithion) and subsequent recovery patterns using normal and probiotic treated feed were also assessed. Three treatments each incorporating three replications were used in the experiment for different days (1, 7, 14, 21, and 28). Treatment T1 was control (0 mg/L), and two concentrations, such as 2.61 mg/L (25 % of 96 h LC50), 5.21 mg/L (50 % of 96 h LC50) were used as Treatment T2 and T3, respectively. After 28 days of exposure to pesticide half of the fishes of T2 and T3 were reared in sumithion free water with normal (T2N, T3N) and probiotic treated feed (T2P, T3P). The median lethal concentration (50 %) for 96 h was 10.42 mg/L. In pesticide-treated groups, values of each hematological parameter (blood glucose, red blood cell, hematocrit, and hemoglobin) decreased but prevalence and severity of micronucleus and white blood cells increased significantly (p< 0.05) with concentration and time duration. Other blood indices including mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were correspondingly changed in comparison to the control. In the recovery experiment, the silver barb recovered spontaneously, but the recovery rate was significantly higher in probiotic treated groups than normally treated groups in time and duration reliant fashion. In conclusion, persistent sublethal dosages of sumithion caused hematological abnormalities in silver barb. Probiotic supplement can recover the damage but only 28 days of recovery is not enough to recover the total alterations. |
| first_indexed | 2024-04-11T06:23:59Z |
| format | Article |
| id | doaj.art-56c5d7513e67403bb9a0da818ca39864 |
| institution | Directory Open Access Journal |
| issn | 2214-7500 |
| language | English |
| last_indexed | 2024-04-11T06:23:59Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Toxicology Reports |
| spelling | doaj.art-56c5d7513e67403bb9a0da818ca398642022-12-22T04:40:26ZengElsevierToxicology Reports2214-75002022-01-019230237Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotusKamrunnaher Kole0Md. Rabiul Islam1Cynthia Elisia Mrong2Nusrat Nahid Neepa3Nargis Sultana4Md. Rezwanul Haque5Sadia Salam6Golam Mohammod Mostakim7Department of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, BangladeshDepartment of Aquaculture, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, BangladeshDepartment of Fisheries Biology and Aquatic Environment, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, 1706, BangladeshDepartment of Biochemistry and Molecular Biology, Bangladesh Agricultural University, Mymensingh, 2202, BangladeshDepartment of Fisheries Biology and Genetics, Bangladesh Agricultural University, Mymensingh, 2202, BangladeshGraduate Training Institute, Bangladesh Agricultural University, Mymensingh, 2202, Bangladesh; Corresponding author.The experiment was conducted to clarify sumithion induced hematoxicity in silver barb (Barbonymus gonionotus) through in vivo exposures (25 % and 50 % of LC50 of sumithion) and subsequent recovery patterns using normal and probiotic treated feed were also assessed. Three treatments each incorporating three replications were used in the experiment for different days (1, 7, 14, 21, and 28). Treatment T1 was control (0 mg/L), and two concentrations, such as 2.61 mg/L (25 % of 96 h LC50), 5.21 mg/L (50 % of 96 h LC50) were used as Treatment T2 and T3, respectively. After 28 days of exposure to pesticide half of the fishes of T2 and T3 were reared in sumithion free water with normal (T2N, T3N) and probiotic treated feed (T2P, T3P). The median lethal concentration (50 %) for 96 h was 10.42 mg/L. In pesticide-treated groups, values of each hematological parameter (blood glucose, red blood cell, hematocrit, and hemoglobin) decreased but prevalence and severity of micronucleus and white blood cells increased significantly (p< 0.05) with concentration and time duration. Other blood indices including mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were correspondingly changed in comparison to the control. In the recovery experiment, the silver barb recovered spontaneously, but the recovery rate was significantly higher in probiotic treated groups than normally treated groups in time and duration reliant fashion. In conclusion, persistent sublethal dosages of sumithion caused hematological abnormalities in silver barb. Probiotic supplement can recover the damage but only 28 days of recovery is not enough to recover the total alterations.http://www.sciencedirect.com/science/article/pii/S221475002200018XHematoxicitySublethalLC50ProbioticIn vivo exposuresRecovery |
| spellingShingle | Kamrunnaher Kole Md. Rabiul Islam Cynthia Elisia Mrong Nusrat Nahid Neepa Nargis Sultana Md. Rezwanul Haque Sadia Salam Golam Mohammod Mostakim Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus Toxicology Reports Hematoxicity Sublethal LC50 Probiotic In vivo exposures Recovery |
| title | Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus |
| title_full | Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus |
| title_fullStr | Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus |
| title_full_unstemmed | Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus |
| title_short | Toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in Barbonymus gonionotus |
| title_sort | toxicological effect of sumithion pesticide on the hematological parameters and its recovery pattern using probiotic in barbonymus gonionotus |
| topic | Hematoxicity Sublethal LC50 Probiotic In vivo exposures Recovery |
| url | http://www.sciencedirect.com/science/article/pii/S221475002200018X |
| work_keys_str_mv | AT kamrunnaherkole toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT mdrabiulislam toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT cynthiaelisiamrong toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT nusratnahidneepa toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT nargissultana toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT mdrezwanulhaque toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT sadiasalam toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus AT golammohammodmostakim toxicologicaleffectofsumithionpesticideonthehematologicalparametersanditsrecoverypatternusingprobioticinbarbonymusgonionotus |