The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI)
Background: Heart rate variability (HRV) could have independent and critical prognostic values in patients admitted for ST segment elevation myocardial infarction (STEMI). There are limited data in the literature regarding HRV assessment in STEMI setting. Thus, we aim to investigate the potential co...
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MDPI AG
2022-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/22/9/3571 |
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| author | Crischentian Brinza Mariana Floria Adrian Covic Andreea Covic Dragos-Viorel Scripcariu Alexandru Burlacu |
| author_facet | Crischentian Brinza Mariana Floria Adrian Covic Andreea Covic Dragos-Viorel Scripcariu Alexandru Burlacu |
| author_sort | Crischentian Brinza |
| collection | DOAJ |
| description | Background: Heart rate variability (HRV) could have independent and critical prognostic values in patients admitted for ST segment elevation myocardial infarction (STEMI). There are limited data in the literature regarding HRV assessment in STEMI setting. Thus, we aim to investigate the potential correlations between HRV and adverse outcomes in a contemporary cohort of patients presenting with STEMI undergoing primary percutaneous coronary intervention (PCI). Methods: We will perform a prospective, observational cohort study in a single healthcare center. Adult patients aged ≥18 years presenting with STEMI in sinus rhythm will be enrolled for primary PCI within 12 h from symptoms onset. Time domain, frequency domain, and nonlinear HRV parameters will be measured using a medically approved wrist-wearable device for 5 min segments during myocardial revascularization by primary PCI. Additional HRV measurements will be performed one and six months from the index event. The primary composite outcome will include all-cause mortality and major adverse cardiovascular events (during the hospital stay, one month, and one year following admission). Several secondary outcomes will be analyzed: individual components of the primary composite outcome, target lesion revascularization, hospitalizations for heart failure, ventricular arrhythmias, left ventricular ejection fraction, and left ventricular diastolic function. Conclusions: Our study will enlighten the reliability and usefulness of HRV evaluation as a prognostic marker in contemporary patients with STEMI. The potential validation of HRV as a risk marker for adverse outcomes following STEMI will ensure a background for including HRV parameters in future risk scores and guidelines. |
| first_indexed | 2024-03-10T03:39:59Z |
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| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T03:39:59Z |
| publishDate | 2022-05-01 |
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| record_format | Article |
| series | Sensors |
| spelling | doaj.art-56c5ef588d0b44f39bb99c4f3838521a2023-11-23T09:20:24ZengMDPI AGSensors1424-82202022-05-01229357110.3390/s22093571The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI)Crischentian Brinza0Mariana Floria1Adrian Covic2Andreea Covic3Dragos-Viorel Scripcariu4Alexandru Burlacu5Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, RomaniaBackground: Heart rate variability (HRV) could have independent and critical prognostic values in patients admitted for ST segment elevation myocardial infarction (STEMI). There are limited data in the literature regarding HRV assessment in STEMI setting. Thus, we aim to investigate the potential correlations between HRV and adverse outcomes in a contemporary cohort of patients presenting with STEMI undergoing primary percutaneous coronary intervention (PCI). Methods: We will perform a prospective, observational cohort study in a single healthcare center. Adult patients aged ≥18 years presenting with STEMI in sinus rhythm will be enrolled for primary PCI within 12 h from symptoms onset. Time domain, frequency domain, and nonlinear HRV parameters will be measured using a medically approved wrist-wearable device for 5 min segments during myocardial revascularization by primary PCI. Additional HRV measurements will be performed one and six months from the index event. The primary composite outcome will include all-cause mortality and major adverse cardiovascular events (during the hospital stay, one month, and one year following admission). Several secondary outcomes will be analyzed: individual components of the primary composite outcome, target lesion revascularization, hospitalizations for heart failure, ventricular arrhythmias, left ventricular ejection fraction, and left ventricular diastolic function. Conclusions: Our study will enlighten the reliability and usefulness of HRV evaluation as a prognostic marker in contemporary patients with STEMI. The potential validation of HRV as a risk marker for adverse outcomes following STEMI will ensure a background for including HRV parameters in future risk scores and guidelines.https://www.mdpi.com/1424-8220/22/9/3571ST elevation myocardial infarctionheart rate variabilitypercutaneous coronary interventionprognosisprospective studyrisk factors |
| spellingShingle | Crischentian Brinza Mariana Floria Adrian Covic Andreea Covic Dragos-Viorel Scripcariu Alexandru Burlacu The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) Sensors ST elevation myocardial infarction heart rate variability percutaneous coronary intervention prognosis prospective study risk factors |
| title | The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) |
| title_full | The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) |
| title_fullStr | The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) |
| title_full_unstemmed | The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) |
| title_short | The Usefulness of Assessing Heart Rate Variability in Patients with Acute Myocardial Infarction (HeaRt-V-AMI) |
| title_sort | usefulness of assessing heart rate variability in patients with acute myocardial infarction heart v ami |
| topic | ST elevation myocardial infarction heart rate variability percutaneous coronary intervention prognosis prospective study risk factors |
| url | https://www.mdpi.com/1424-8220/22/9/3571 |
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