Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis
Neonatal hypoglycemia is one of the major complications in neonatal wards, requiring rapid diagnosis and treatment to prevent its complications. Dextrose gel is used as a cheap and safe choice. Thus, the present systematic review and meta-analysis study aimed to investigate the effects of oral dextr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2022-07-01
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| Series: | Journal of Pediatrics Review |
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| Online Access: | http://jpr.mazums.ac.ir/article-1-465-en.html |
| _version_ | 1811255592866545664 |
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| author | Moloud Fakhri Roya Farhadi Seydeh Sedigheh Yousefi Mahmood Moosazadeh Melina Ramezanpour Mohammad Azadbakht |
| author_facet | Moloud Fakhri Roya Farhadi Seydeh Sedigheh Yousefi Mahmood Moosazadeh Melina Ramezanpour Mohammad Azadbakht |
| author_sort | Moloud Fakhri |
| collection | DOAJ |
| description | Neonatal hypoglycemia is one of the major complications in neonatal wards, requiring rapid diagnosis and treatment to prevent its complications. Dextrose gel is used as a cheap and safe choice. Thus, the present systematic review and meta-analysis study aimed to investigate the effects of oral dextrose gel in preventing and treating neonatal hypoglycemia. To find the relevant articles, the national databases, including Barekat Gostar, SID, Magiran, IranDoc, and international databases, including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar were consulted with standard keywords. The data were analyzed using the STATA 14 software, while the P value < 0.05 was considered significant. In 9 articles with a sample size of 8755 neonates, the mean neonatal weight ranged from 2890 to 3669 g. The share of neonates born through normal vaginal delivery equaled 61%, while 16% had low birth weight (below 2500 g), 16% had high birth weight (above 4500 g), 51% had diabetic mothers, 20% were premature, and 88% were singleton. Oral dextrose gel reduced the risk of neonatal hypoglycemia by OR=0.83 (95% CI: 0.75-0.93). However, neonatal hypoglycemia treatment with oral dextrose gel had an OR=0.78 (95% CI: 0.57-1.07), which was not statistically significant. Oral dextrose gel was effective in preventing neonatal hypoglycemia. |
| first_indexed | 2024-04-12T17:27:25Z |
| format | Article |
| id | doaj.art-56c6214ad9f14dc4afa9a8dee02c5798 |
| institution | Directory Open Access Journal |
| issn | 2322-4398 2322-4401 |
| language | English |
| last_indexed | 2024-04-12T17:27:25Z |
| publishDate | 2022-07-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj.art-56c6214ad9f14dc4afa9a8dee02c57982022-12-22T03:23:16ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012022-07-01103191202Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysisMoloud Fakhri0Roya Farhadi1Seydeh Sedigheh Yousefi2Mahmood Moosazadeh3Melina Ramezanpour4Mohammad Azadbakht5 Mazandaran University of Medical Sciences, Mazandaran, Iran. Mazandaran University of Medical Sciences, Mazandaran, Iran. Mazandaran University of Medical Sciences, Mazandaran, Iran. Mazandaran University of Medical Sciences, Mazandaran, Iran. Mazandaran University of Medical Sciences, Mazandaran, Iran. Mazandaran University of Medical Sciences, Mazandaran, Iran. Neonatal hypoglycemia is one of the major complications in neonatal wards, requiring rapid diagnosis and treatment to prevent its complications. Dextrose gel is used as a cheap and safe choice. Thus, the present systematic review and meta-analysis study aimed to investigate the effects of oral dextrose gel in preventing and treating neonatal hypoglycemia. To find the relevant articles, the national databases, including Barekat Gostar, SID, Magiran, IranDoc, and international databases, including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar were consulted with standard keywords. The data were analyzed using the STATA 14 software, while the P value < 0.05 was considered significant. In 9 articles with a sample size of 8755 neonates, the mean neonatal weight ranged from 2890 to 3669 g. The share of neonates born through normal vaginal delivery equaled 61%, while 16% had low birth weight (below 2500 g), 16% had high birth weight (above 4500 g), 51% had diabetic mothers, 20% were premature, and 88% were singleton. Oral dextrose gel reduced the risk of neonatal hypoglycemia by OR=0.83 (95% CI: 0.75-0.93). However, neonatal hypoglycemia treatment with oral dextrose gel had an OR=0.78 (95% CI: 0.57-1.07), which was not statistically significant. Oral dextrose gel was effective in preventing neonatal hypoglycemia.http://jpr.mazums.ac.ir/article-1-465-en.htmldextrose gelpreventiontherapyhypoglycemiainfantnewborn |
| spellingShingle | Moloud Fakhri Roya Farhadi Seydeh Sedigheh Yousefi Mahmood Moosazadeh Melina Ramezanpour Mohammad Azadbakht Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis Journal of Pediatrics Review dextrose gel prevention therapy hypoglycemia infant newborn |
| title | Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis |
| title_full | Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis |
| title_fullStr | Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis |
| title_full_unstemmed | Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis |
| title_short | Effects of Dextrose Gel in Preventing and Treating Neonatal Hypoglycemia: A Systematic Review and Meta-analysis |
| title_sort | effects of dextrose gel in preventing and treating neonatal hypoglycemia a systematic review and meta analysis |
| topic | dextrose gel prevention therapy hypoglycemia infant newborn |
| url | http://jpr.mazums.ac.ir/article-1-465-en.html |
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