Fibrin Membrane Pupillary-Block Glaucoma After Uneventful Cataract Surgery Treated with Intracameral Tissue Plasminogen Activator: A Case Report

Objective: To evaluate the diagnostic and therapeutic methods of fibrindependent pupillary-block glaucoma (PBG).Methods: A 79-year-old male patient with hypertension was admitted to hospital with symptoms of pain and redness 6 days after an uneventful cataract surgery.Results: He had acute elevation...

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Bibliographic Details
Main Authors: Tülay Alpar Akçetin, Kadir Eltutar, Nurhan Dinçer, Fatma Esin Özdemir
Format: Article
Language:English
Published: Galenos Yayinevi 2015-03-01
Series:İstanbul Medical Journal
Subjects:
Online Access: http://imj.galenos.com.tr/archives/archive-detail/article-preview/fibrin-membrane-pupillary-block-glaucoma-after-une/21017
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Summary:Objective: To evaluate the diagnostic and therapeutic methods of fibrindependent pupillary-block glaucoma (PBG).Methods: A 79-year-old male patient with hypertension was admitted to hospital with symptoms of pain and redness 6 days after an uneventful cataract surgery.Results: He had acute elevation of intraocular pressure with a shallow anterior chamber. Because of severe corneal edema, the anterior chamber details could not be distinguished. After systemic and topical antiglaucoma treatment, corneal edema was reduced and a complete fibrin membrane was observed across the pupil on slit lamp examination. A complete fibrin membrane across the pupillary space, shallow anterior chamber, and deep posterior chamber was confirmed by ultrasonic biomicroscopy (UBM). The intraocular lens (IOL) was actually displaced posteriorly, with a large clear space between the IOL and iris. Despite topical and subconjunctival corticosteroid therapy as well as Nd:YAG laser membranotomy, the fibrin membrane was not resolved. Tissue plasminogen activator (tPA) (25 μg) was injected intracamerally and the fibrin membrane was completely dissolved, improving the pupillar block.Conclusion: Anterior segment imaging techniques, especially UBM, are a powerful diagnostic technique for differentiating the technique for the analysis of the mechanisms underlying acute angle-closure glaucoma mechanism. Fibrin-dependent PBG was successfully treated with an intracameral injection of tPA.
ISSN:2619-9793
2148-094X