Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates

Viral infections are among the most complex medical problems and have been a major threat to the economy and global health. Several epidemics and pandemics have occurred due to viruses, which has led to a significant increase in mortality and morbidity rates. Natural products have always been an ins...

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Main Authors: Eyana Thomas, Laura E. Stewart, Brien A. Darley, Ashley M. Pham, Isabella Esteban, Siva S. Panda
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/20/6197
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author Eyana Thomas
Laura E. Stewart
Brien A. Darley
Ashley M. Pham
Isabella Esteban
Siva S. Panda
author_facet Eyana Thomas
Laura E. Stewart
Brien A. Darley
Ashley M. Pham
Isabella Esteban
Siva S. Panda
author_sort Eyana Thomas
collection DOAJ
description Viral infections are among the most complex medical problems and have been a major threat to the economy and global health. Several epidemics and pandemics have occurred due to viruses, which has led to a significant increase in mortality and morbidity rates. Natural products have always been an inspiration and source for new drug development because of their various uses. Among all-natural sources, plant sources are the most dominant for the discovery of new therapeutic agents due to their chemical and structural diversity. Despite the traditional use and potential source for drug development, natural products have gained little attention from large pharmaceutical industries. Several plant extracts and isolated compounds have been extensively studied and explored for antiviral properties against different strains of viruses. In this review, we have compiled antiviral plant extracts and natural products isolated from plants reported since 2015.
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spelling doaj.art-56c821250d7e4a6fbdb31987ae5873862023-11-22T19:19:40ZengMDPI AGMolecules1420-30492021-10-012620619710.3390/molecules26206197Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug CandidatesEyana Thomas0Laura E. Stewart1Brien A. Darley2Ashley M. Pham3Isabella Esteban4Siva S. Panda5Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USADepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USADepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USADepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USADepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USADepartment of Chemistry & Physics, Augusta University, Augusta, GA 30912, USAViral infections are among the most complex medical problems and have been a major threat to the economy and global health. Several epidemics and pandemics have occurred due to viruses, which has led to a significant increase in mortality and morbidity rates. Natural products have always been an inspiration and source for new drug development because of their various uses. Among all-natural sources, plant sources are the most dominant for the discovery of new therapeutic agents due to their chemical and structural diversity. Despite the traditional use and potential source for drug development, natural products have gained little attention from large pharmaceutical industries. Several plant extracts and isolated compounds have been extensively studied and explored for antiviral properties against different strains of viruses. In this review, we have compiled antiviral plant extracts and natural products isolated from plants reported since 2015.https://www.mdpi.com/1420-3049/26/20/6197natural productsextractsmechanism of actionantiviral activitydrug development
spellingShingle Eyana Thomas
Laura E. Stewart
Brien A. Darley
Ashley M. Pham
Isabella Esteban
Siva S. Panda
Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
Molecules
natural products
extracts
mechanism of action
antiviral activity
drug development
title Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
title_full Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
title_fullStr Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
title_full_unstemmed Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
title_short Plant-Based Natural Products and Extracts: Potential Source to Develop New Antiviral Drug Candidates
title_sort plant based natural products and extracts potential source to develop new antiviral drug candidates
topic natural products
extracts
mechanism of action
antiviral activity
drug development
url https://www.mdpi.com/1420-3049/26/20/6197
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