3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways

3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways

Context: Seaweeds are rich in bioactive compounds in the form of vitamins, phycobilins, polyphenols, carotenoids, phycocyanins and polysaccharides; many of these are known to have advantageous applications in human health. 3-Hydroxy-4,7-megastigmadien-9-one (comp) was isolated from Ulva pertusa (U....

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Bibliographic Details
Main Authors: Irshad Ali, Zahid Manzoor, Jung-Eun Koo, Jung-Eun Kim, Sang-Hee Byeon, Eun-Sook Yoo, Hee-Kyoung Kang, Jin-Won Hyun, Nam-Ho Lee, Young-Sang Koh
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
pro-inflammatory cytokines
mitogen-activated protein kinase
bmdcs
cpg-dna
Online Access:http://dx.doi.org/10.1080/13880209.2016.1246574

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