Adverse Drug Reactions in the Oral Cavity
Every medication may lead to adverse effects, even when used in standard doses and mode of application. In the oral cavity, adverse effects may affect every part of oral mucosa and are the result of medications taken either locally or systemically. Oral adverse reactions to drugs are not typical and...
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2015-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | http://hrcak.srce.hr/file/214442 |
| _version_ | 1811252634449870848 |
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| author | Danko Velimir Vrdoljak Vanja Vučićević Boras Vlaho Brailo Sonja Kraljević Šimunković Dragana Gabrić Ana Andabak-Rogulj |
| author_facet | Danko Velimir Vrdoljak Vanja Vučićević Boras Vlaho Brailo Sonja Kraljević Šimunković Dragana Gabrić Ana Andabak-Rogulj |
| author_sort | Danko Velimir Vrdoljak |
| collection | DOAJ |
| description | Every medication may lead to adverse effects, even when used in standard doses and mode of application. In the oral cavity, adverse effects may affect every part of oral mucosa and are the result of medications taken either locally or systemically. Oral adverse reactions to drugs are not typical and therefore sometimes not easy to recognize. On diagnosing adverse side effects in the oral cavity, experienced clinician will usually diagnose the condition on the basis of detailed medical history and clinical finding. However, the only objective evidence for the offending drug is ‘re-challenge’, i.e. exposure to the drug after its discontinuation. It carries a huge risk of anaphylactic reaction; therefore it has to be performed in a controlled hospital setting. Therapy is based on immediate exclusion of the offending drug and, if lesions are present in the oral cavity, topical or systemic corticosteroid therapy is prescribed. This article gives a review of patients with oral adverse drug reactions referred to the Department of Oral Medicine in Zagreb. |
| first_indexed | 2024-04-12T16:37:33Z |
| format | Article |
| id | doaj.art-56ccf840e5174d3db1eb617dc9ddb82d |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-12T16:37:33Z |
| publishDate | 2015-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-56ccf840e5174d3db1eb617dc9ddb82d2022-12-22T03:24:55ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512015-01-0154.2.208215Adverse Drug Reactions in the Oral CavityDanko Velimir Vrdoljak0Vanja Vučićević Boras1Vlaho Brailo2Sonja Kraljević Šimunković3Dragana Gabrić4Ana Andabak-Rogulj5Clinical Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartment of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb, CroatiaDepartment of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, CroatiaEvery medication may lead to adverse effects, even when used in standard doses and mode of application. In the oral cavity, adverse effects may affect every part of oral mucosa and are the result of medications taken either locally or systemically. Oral adverse reactions to drugs are not typical and therefore sometimes not easy to recognize. On diagnosing adverse side effects in the oral cavity, experienced clinician will usually diagnose the condition on the basis of detailed medical history and clinical finding. However, the only objective evidence for the offending drug is ‘re-challenge’, i.e. exposure to the drug after its discontinuation. It carries a huge risk of anaphylactic reaction; therefore it has to be performed in a controlled hospital setting. Therapy is based on immediate exclusion of the offending drug and, if lesions are present in the oral cavity, topical or systemic corticosteroid therapy is prescribed. This article gives a review of patients with oral adverse drug reactions referred to the Department of Oral Medicine in Zagreb.http://hrcak.srce.hr/file/214442Pharmaceutical preparations – adverse effectsOral manifestations – diagnosisOral manifestations – therapy |
| spellingShingle | Danko Velimir Vrdoljak Vanja Vučićević Boras Vlaho Brailo Sonja Kraljević Šimunković Dragana Gabrić Ana Andabak-Rogulj Adverse Drug Reactions in the Oral Cavity Acta Clinica Croatica Pharmaceutical preparations – adverse effects Oral manifestations – diagnosis Oral manifestations – therapy |
| title | Adverse Drug Reactions in the Oral Cavity |
| title_full | Adverse Drug Reactions in the Oral Cavity |
| title_fullStr | Adverse Drug Reactions in the Oral Cavity |
| title_full_unstemmed | Adverse Drug Reactions in the Oral Cavity |
| title_short | Adverse Drug Reactions in the Oral Cavity |
| title_sort | adverse drug reactions in the oral cavity |
| topic | Pharmaceutical preparations – adverse effects Oral manifestations – diagnosis Oral manifestations – therapy |
| url | http://hrcak.srce.hr/file/214442 |
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