Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases
Canonical transient receptor potential(TRPC) is a kind of non-selective cation channel located in the cell membrane, which plays an important role in electrophysiological activity of cells. Under pathological conditions, TRPC channels are more selective for Ca2+, which will break the Ca2+ homeostasi...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-08-01
|
| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-8-1309.pdf |
| _version_ | 1797366344539176960 |
|---|---|
| author | XIE Dongge, LI Junhao, HAN Han, LI Shoutian |
| author_facet | XIE Dongge, LI Junhao, HAN Han, LI Shoutian |
| author_sort | XIE Dongge, LI Junhao, HAN Han, LI Shoutian |
| collection | DOAJ |
| description | Canonical transient receptor potential(TRPC) is a kind of non-selective cation channel located in the cell membrane, which plays an important role in electrophysiological activity of cells. Under pathological conditions, TRPC channels are more selective for Ca2+, which will break the Ca2+ homeostasis in skeletal muscle cells and lead to calcium overload and subsequent occurrence of a variety of skeletal muscle diseases. To study the role and mechanism of TRPC channels in skeletal muscle diseases is helpful to provide new ideas for disease treatment. |
| first_indexed | 2024-03-08T17:02:55Z |
| format | Article |
| id | doaj.art-56cfc6e3f3244887a144414289be05f3 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T17:02:55Z |
| publishDate | 2023-08-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-56cfc6e3f3244887a144414289be05f32024-01-04T07:33:24ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252023-08-014381309131210.16352/j.issn.1001-6325.2023.08.1309Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseasesXIE Dongge, LI Junhao, HAN Han, LI Shoutian0Department of Forensic Pathology,School of Forensic Medicine, Zunyi Medical University, Zunyi 563000, ChinaCanonical transient receptor potential(TRPC) is a kind of non-selective cation channel located in the cell membrane, which plays an important role in electrophysiological activity of cells. Under pathological conditions, TRPC channels are more selective for Ca2+, which will break the Ca2+ homeostasis in skeletal muscle cells and lead to calcium overload and subsequent occurrence of a variety of skeletal muscle diseases. To study the role and mechanism of TRPC channels in skeletal muscle diseases is helpful to provide new ideas for disease treatment.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-8-1309.pdfcanonical transient receptor potential(trpc) channel|skeletal muscle|skeletal muscle diseases|calcium ions |
| spellingShingle | XIE Dongge, LI Junhao, HAN Han, LI Shoutian Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases Jichu yixue yu linchuang canonical transient receptor potential(trpc) channel|skeletal muscle|skeletal muscle diseases|calcium ions |
| title | Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| title_full | Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| title_fullStr | Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| title_full_unstemmed | Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| title_short | Research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| title_sort | research progress on the role of canonical transient receptor potential channels in skeletal muscle diseases |
| topic | canonical transient receptor potential(trpc) channel|skeletal muscle|skeletal muscle diseases|calcium ions |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-8-1309.pdf |
| work_keys_str_mv | AT xiedonggelijunhaohanhanlishoutian researchprogressontheroleofcanonicaltransientreceptorpotentialchannelsinskeletalmusclediseases |