Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent
Abstract The activity and capacity of gallic acid (GA) and methyl gallate (MG) in scavenging DPPH· were determined in different solvents. Based on the bimolecular rate constants k 2, both antioxidants showed highest activities in EtOH, followed by in MeOH, t-BuOH, MeCN, 2-PrOH, acetone, THF, ethyl a...
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| Format: | Article |
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Nature Portfolio
2022-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-12803-3 |
| _version_ | 1811324549136908288 |
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| author | Marzieh Sadat Shojaee Marzieh Moeenfard Reza Farhoosh |
| author_facet | Marzieh Sadat Shojaee Marzieh Moeenfard Reza Farhoosh |
| author_sort | Marzieh Sadat Shojaee |
| collection | DOAJ |
| description | Abstract The activity and capacity of gallic acid (GA) and methyl gallate (MG) in scavenging DPPH· were determined in different solvents. Based on the bimolecular rate constants k 2, both antioxidants showed highest activities in EtOH, followed by in MeOH, t-BuOH, MeCN, 2-PrOH, acetone, THF, ethyl acetate, and 1,4-dioxane. GA indicated better activities (k 2 value, M−1 s−1) than MG in the alcoholic solvents (51–1939 vs. 25–1530) and in MeCN (203 vs. 187) whereas MG was of higher activities in the polar aprotic solvents (1.7–41 vs. 1.6–13). The highest stoichiometries for GA vs. MG were in 2-PrOH (6.67 vs. 5.37), followed by EtOH (5.84 vs. 4.57), MeOH (5.34 vs. 3.8) ~ acetone (5.02 vs. 4.44), MeCN (3.68 vs. 3.05) ~ t-BuOH (3.14 vs. 2.99), THF (2.34 vs. 2.2), ethyl acetate (1.2 vs. 0.93), and 1,4-dioxane (0.34 vs. 0.35). |
| first_indexed | 2024-04-13T14:16:19Z |
| format | Article |
| id | doaj.art-56d01582243b4688b06168d174ca0892 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T14:16:19Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-56d01582243b4688b06168d174ca08922022-12-22T02:43:38ZengNature PortfolioScientific Reports2045-23222022-05-011211910.1038/s41598-022-12803-3Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solventMarzieh Sadat Shojaee0Marzieh Moeenfard1Reza Farhoosh2Department of Food Science and Technology, Ferdowsi University of Mashhad, Faculty of AgricultureDepartment of Food Science and Technology, Ferdowsi University of Mashhad, Faculty of AgricultureDepartment of Food Science and Technology, Ferdowsi University of Mashhad, Faculty of AgricultureAbstract The activity and capacity of gallic acid (GA) and methyl gallate (MG) in scavenging DPPH· were determined in different solvents. Based on the bimolecular rate constants k 2, both antioxidants showed highest activities in EtOH, followed by in MeOH, t-BuOH, MeCN, 2-PrOH, acetone, THF, ethyl acetate, and 1,4-dioxane. GA indicated better activities (k 2 value, M−1 s−1) than MG in the alcoholic solvents (51–1939 vs. 25–1530) and in MeCN (203 vs. 187) whereas MG was of higher activities in the polar aprotic solvents (1.7–41 vs. 1.6–13). The highest stoichiometries for GA vs. MG were in 2-PrOH (6.67 vs. 5.37), followed by EtOH (5.84 vs. 4.57), MeOH (5.34 vs. 3.8) ~ acetone (5.02 vs. 4.44), MeCN (3.68 vs. 3.05) ~ t-BuOH (3.14 vs. 2.99), THF (2.34 vs. 2.2), ethyl acetate (1.2 vs. 0.93), and 1,4-dioxane (0.34 vs. 0.35).https://doi.org/10.1038/s41598-022-12803-3 |
| spellingShingle | Marzieh Sadat Shojaee Marzieh Moeenfard Reza Farhoosh Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent Scientific Reports |
| title | Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent |
| title_full | Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent |
| title_fullStr | Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent |
| title_full_unstemmed | Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent |
| title_short | Kinetics and stoichiometry of gallic acid and methyl gallate in scavenging DPPH radical as affected by the reaction solvent |
| title_sort | kinetics and stoichiometry of gallic acid and methyl gallate in scavenging dpph radical as affected by the reaction solvent |
| url | https://doi.org/10.1038/s41598-022-12803-3 |
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