Value of lyophilized morphine in myocardial revascularization
Introduction: epidural analgesia is a mainstay in cardiac surgery. Objectives: The aim of this study was to compare the use of lyophilized morphine and epidural bupivacaine in postoperative analgesia of myocardial revascularization. Method: A comparative and prospective study was conducted in 160 pa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Spanish |
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Editorial Ciencias Médicas
2012-01-01
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| Series: | Acta Médica del Centro |
| Subjects: | |
| Online Access: | http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/671 |
| _version_ | 1811248560269688832 |
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| author | Rudy Hernández Ortega Osvaldo González Alfonso Pedro A. Hidalgo Menéndez Ilida M. Marrero Font Elvis González Pérez Juan Manuel Rodríguez Álvarez |
| author_facet | Rudy Hernández Ortega Osvaldo González Alfonso Pedro A. Hidalgo Menéndez Ilida M. Marrero Font Elvis González Pérez Juan Manuel Rodríguez Álvarez |
| author_sort | Rudy Hernández Ortega |
| collection | DOAJ |
| description | Introduction: epidural analgesia is a mainstay in cardiac surgery. Objectives: The aim of this study was to compare the use of lyophilized morphine and epidural bupivacaine in postoperative analgesia of myocardial revascularization. Method: A comparative and prospective study was conducted in 160 patients. They were divided into two groups: group M received epidural analgesia with morphine (2 mg) associated with 100 mg of bupivacaine, and group B bupivacaine only. Results: there was a prevalence of males. The ages and the average weights of both groups were similar (p>0.05). In group M, 90% of patients had excellent analgesia eight hours after the intervention, and it was good to excellent after 12 and 24 hours. On the other hand, 50% of patients in group B talked of an average analgesia eight hours after the operation –which extended to 80% of patients after 12 hours– and, after 24 hours, all the patients in group B complained of an inadequate or poor analgesia (p<0.05). The average postoperative analgesia obtained in group M was 29.41 hours, and 9.76 hours in group B (p<0.01). The main adverse events were hypotension and bradycardia. Conclusions: Morphine showed its usefulness as an analgesic agent in the surgical operation of the coronary arteries. Patients with epidural bupivacaine and morphine had a better analgesia with longer duration than those treated with bupivacaine only. |
| first_indexed | 2024-04-12T15:30:13Z |
| format | Article |
| id | doaj.art-56d46b47076149a6b2c95520e14f8c36 |
| institution | Directory Open Access Journal |
| issn | 2709-7927 |
| language | Spanish |
| last_indexed | 2024-04-12T15:30:13Z |
| publishDate | 2012-01-01 |
| publisher | Editorial Ciencias Médicas |
| record_format | Article |
| series | Acta Médica del Centro |
| spelling | doaj.art-56d46b47076149a6b2c95520e14f8c362022-12-22T03:27:08ZspaEditorial Ciencias MédicasActa Médica del Centro2709-79272012-01-01615564642Value of lyophilized morphine in myocardial revascularizationRudy Hernández Ortega0Osvaldo González Alfonso1Pedro A. Hidalgo Menéndez2Ilida M. Marrero Font3Elvis González Pérez4Juan Manuel Rodríguez Álvarez5Cardiocentro “Ernesto Che Guevara”, Santa Clara, Villa Clara, CubaCardiocentro “Ernesto Che Guevara”, Santa Clara, Villa Clara, CubaCardiocentro “Ernesto Che Guevara”, Santa Clara, Villa Clara, CubaClínica Estomatológica “Celia Sánchez Manduley”, Santa Clara, Villa Clara, CubaHospital Clínico Quirúrgico “Arnaldo Milián Castro”, Santa Clara, Villa Clara, CubaCardiocentro “Ernesto Che Guevara”, Santa Clara, Villa Clara, CubaIntroduction: epidural analgesia is a mainstay in cardiac surgery. Objectives: The aim of this study was to compare the use of lyophilized morphine and epidural bupivacaine in postoperative analgesia of myocardial revascularization. Method: A comparative and prospective study was conducted in 160 patients. They were divided into two groups: group M received epidural analgesia with morphine (2 mg) associated with 100 mg of bupivacaine, and group B bupivacaine only. Results: there was a prevalence of males. The ages and the average weights of both groups were similar (p>0.05). In group M, 90% of patients had excellent analgesia eight hours after the intervention, and it was good to excellent after 12 and 24 hours. On the other hand, 50% of patients in group B talked of an average analgesia eight hours after the operation –which extended to 80% of patients after 12 hours– and, after 24 hours, all the patients in group B complained of an inadequate or poor analgesia (p<0.05). The average postoperative analgesia obtained in group M was 29.41 hours, and 9.76 hours in group B (p<0.01). The main adverse events were hypotension and bradycardia. Conclusions: Morphine showed its usefulness as an analgesic agent in the surgical operation of the coronary arteries. Patients with epidural bupivacaine and morphine had a better analgesia with longer duration than those treated with bupivacaine only.http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/671revascularización miocárdicamorfina/administración & dosificaciónevaluación de eficacia-efectividad de intervenciones |
| spellingShingle | Rudy Hernández Ortega Osvaldo González Alfonso Pedro A. Hidalgo Menéndez Ilida M. Marrero Font Elvis González Pérez Juan Manuel Rodríguez Álvarez Value of lyophilized morphine in myocardial revascularization Acta Médica del Centro revascularización miocárdica morfina/administración & dosificación evaluación de eficacia-efectividad de intervenciones |
| title | Value of lyophilized morphine in myocardial revascularization |
| title_full | Value of lyophilized morphine in myocardial revascularization |
| title_fullStr | Value of lyophilized morphine in myocardial revascularization |
| title_full_unstemmed | Value of lyophilized morphine in myocardial revascularization |
| title_short | Value of lyophilized morphine in myocardial revascularization |
| title_sort | value of lyophilized morphine in myocardial revascularization |
| topic | revascularización miocárdica morfina/administración & dosificación evaluación de eficacia-efectividad de intervenciones |
| url | http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/671 |
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