Probiotics and their Effects on Metabolic Diseases: An Update
ABSTRACT Probiotics are lactic acid bacteria which are used extensively in therapeutic preparations and added to foods. There are many studies which have demonstrated the effects of probiotics on metabolic diseases. One study has shown the effect of fermented dairy products on the serum cholest...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2013-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/2701/46-%205004_E(C)_PF1(M)_F(P)_PF1(PM)_PFA_(P)_OLF(P)_PFA2(PM)_U_(P).pdf |
| Summary: | ABSTRACT
Probiotics are lactic acid bacteria which are used extensively in
therapeutic preparations and added to foods. There are many
studies which have demonstrated the effects of probiotics on
metabolic diseases. One study has shown the effect of fermented
dairy products on the serum cholesterol, especially with selected
strains of lactic acid bacteria. It has been found that a minute
quantity of the dry culture of Lactobacillus fermentum KC4b, for
example, can remove 14.8 mg of cholesterol from the culture medium. Lactobacilli also play an important role in deconjugating the
bile salts in the intestine to form bile acids and thereby inhibiting
the micelle formation. Probiotics reduce the lipid peroxidation and
improve the lipid metabolism in vivo. The addition of probiotics
to the diet for weeks improved the immune response without the
release of inflammatory cytokines, thereby reducing the onset of
systemic inflammatory induced diabetes. There are evidences
that the differences in the composition of the gut microbiota may
precede the development of obesity in children. This review has
illustrated the potential of probiotics in mediating metabolic diseases via the positive modulation of several different physiological
systems, apart from its conventional benefits for the gastrointestinal health. |
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| ISSN: | 2249-782X 0973-709X |