Microscopy techniques for protocell characterization

Recent advances have witnessed the research progress of synthetic preliminary forms of cell-like entities (protocells) towards understanding the origin of life. Microscopy techniques have been instrumental to study protocells both in structural characterization and biomimetic functions. Advanced mic...

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Main Authors: Hua Wu, Yan Qiao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Polymer Testing
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0142941820321644
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author Hua Wu
Yan Qiao
author_facet Hua Wu
Yan Qiao
author_sort Hua Wu
collection DOAJ
description Recent advances have witnessed the research progress of synthetic preliminary forms of cell-like entities (protocells) towards understanding the origin of life. Microscopy techniques have been instrumental to study protocells both in structural characterization and biomimetic functions. Advanced microscopes equipped with different illumination sources (light or electron) and detectors, have provided a versatile platform to investigate the thermodynamic and kinetic behaviors of protocells across a range of scales. Understanding the functions and advantages of each technique is a prerequisite for researchers to obtain high quality microscopic images and extract in-depth structural information. To this end, we provide a brief overview of the applications of microscopic techniques in characterizing protocells, together with discussion of their advantages and drawbacks.
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spelling doaj.art-56e2569e655f4e5485bb6eff421388eb2022-12-21T20:47:04ZengElsevierPolymer Testing0142-94182021-01-0193106935Microscopy techniques for protocell characterizationHua Wu0Yan Qiao1Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China; University of Chinese Academy of Sciences, Beijing, 100049, ChinaBeijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Corresponding author. Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.Recent advances have witnessed the research progress of synthetic preliminary forms of cell-like entities (protocells) towards understanding the origin of life. Microscopy techniques have been instrumental to study protocells both in structural characterization and biomimetic functions. Advanced microscopes equipped with different illumination sources (light or electron) and detectors, have provided a versatile platform to investigate the thermodynamic and kinetic behaviors of protocells across a range of scales. Understanding the functions and advantages of each technique is a prerequisite for researchers to obtain high quality microscopic images and extract in-depth structural information. To this end, we provide a brief overview of the applications of microscopic techniques in characterizing protocells, together with discussion of their advantages and drawbacks.http://www.sciencedirect.com/science/article/pii/S0142941820321644ProtocellCharacterizationMicroscopyMicrocompartmentBiomedical materials
spellingShingle Hua Wu
Yan Qiao
Microscopy techniques for protocell characterization
Polymer Testing
Protocell
Characterization
Microscopy
Microcompartment
Biomedical materials
title Microscopy techniques for protocell characterization
title_full Microscopy techniques for protocell characterization
title_fullStr Microscopy techniques for protocell characterization
title_full_unstemmed Microscopy techniques for protocell characterization
title_short Microscopy techniques for protocell characterization
title_sort microscopy techniques for protocell characterization
topic Protocell
Characterization
Microscopy
Microcompartment
Biomedical materials
url http://www.sciencedirect.com/science/article/pii/S0142941820321644
work_keys_str_mv AT huawu microscopytechniquesforprotocellcharacterization
AT yanqiao microscopytechniquesforprotocellcharacterization