Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging
Background: In radiation therapy, determining the location of the tumor accurately is one of the most important requirements. But, lung tumors due to respiratory motion during radiotherapy are not fixed in a single location and move. Due to limitations in assessing such movements, using a lung phant...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Isfahan University of Medical Sciences
2015-07-01
|
| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/4753 |
| _version_ | 1827851272265400320 |
|---|---|
| author | Zahra Akmali Daryoush Shahbazi-Gahrouei Mohammad Amin Mosleh-Shirazi Milad Baradaran-Ghahfarokhi Nader Fallahian Sadegh Sherkat |
| author_facet | Zahra Akmali Daryoush Shahbazi-Gahrouei Mohammad Amin Mosleh-Shirazi Milad Baradaran-Ghahfarokhi Nader Fallahian Sadegh Sherkat |
| author_sort | Zahra Akmali |
| collection | DOAJ |
| description | Background: In radiation therapy, determining the location of the tumor accurately is one of the most important requirements. But, lung tumors due to respiratory motion during radiotherapy are not fixed in a single location and move. Due to limitations in assessing such movements, using a lung phantom can be useful and operational in fast, easy and inexpensive assessment of such movements. The aim of this study was to design and build a four-dimensional respiratory phantom for studying tumor movement in radiation therapy.
Methods: By molding the normal human lung, artificial lung was made of silicon. The chest was made of plexiglas and a double-walled container. The wall was filled with water to increase the signal strength of Magnetic Resonance Imaging (MRI). A 1.5-liter thin bag of silicon was made as the synthetic diaphragm and was placed into the chest. A piston pump was used to simulate the breathing and an engine and gearbox were used to create the reciprocating motion. Finally, the silicon lung model, capable of simulating the natural movement of the human lung was built with 7 tumors in it.
Findings: The four-dimensional phantom lung was designed and constructed for examining the tumor motion during radiotherapy while breathing, according to the images obtained from the lung for examining the motion and the types of movements of the lung.
Conclusion: It can be declared that this artificial lung (phantom), unlike the previously designed ones, is largely similar to human lungs and can be a useful tool for quality control of the imagine devices and the new protocols of radiotherapy. |
| first_indexed | 2024-03-12T10:29:41Z |
| format | Article |
| id | doaj.art-56e2712cb84543f29660f06874f2a5ac |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T10:29:41Z |
| publishDate | 2015-07-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-56e2712cb84543f29660f06874f2a5ac2023-09-02T09:20:36ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2015-07-01333336316421867Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance ImagingZahra Akmali0Daryoush Shahbazi-Gahrouei1Mohammad Amin Mosleh-Shirazi2Milad Baradaran-Ghahfarokhi3Nader Fallahian4Sadegh Sherkat5MSc Student, Department of Medical Physics, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranProfessor, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Medical Imaging Research Center AND Department of Radiotherapy and Oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranPhD Student, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranPhD Student, Department of Orthotics and Prosthetics, University of Social Welfare and Rehabilitation Sciences, Tehran, IranDepartment of Mechanical Construction, Islamic Azad University, Najafabad Branch, Isfahan, IranBackground: In radiation therapy, determining the location of the tumor accurately is one of the most important requirements. But, lung tumors due to respiratory motion during radiotherapy are not fixed in a single location and move. Due to limitations in assessing such movements, using a lung phantom can be useful and operational in fast, easy and inexpensive assessment of such movements. The aim of this study was to design and build a four-dimensional respiratory phantom for studying tumor movement in radiation therapy. Methods: By molding the normal human lung, artificial lung was made of silicon. The chest was made of plexiglas and a double-walled container. The wall was filled with water to increase the signal strength of Magnetic Resonance Imaging (MRI). A 1.5-liter thin bag of silicon was made as the synthetic diaphragm and was placed into the chest. A piston pump was used to simulate the breathing and an engine and gearbox were used to create the reciprocating motion. Finally, the silicon lung model, capable of simulating the natural movement of the human lung was built with 7 tumors in it. Findings: The four-dimensional phantom lung was designed and constructed for examining the tumor motion during radiotherapy while breathing, according to the images obtained from the lung for examining the motion and the types of movements of the lung. Conclusion: It can be declared that this artificial lung (phantom), unlike the previously designed ones, is largely similar to human lungs and can be a useful tool for quality control of the imagine devices and the new protocols of radiotherapy.http://jims.mui.ac.ir/index.php/jims/article/view/4753Moving phantomMagnetic resonance imagingRadiotherapyLung |
| spellingShingle | Zahra Akmali Daryoush Shahbazi-Gahrouei Mohammad Amin Mosleh-Shirazi Milad Baradaran-Ghahfarokhi Nader Fallahian Sadegh Sherkat Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging مجله دانشکده پزشکی اصفهان Moving phantom Magnetic resonance imaging Radiotherapy Lung |
| title | Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging |
| title_full | Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging |
| title_fullStr | Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging |
| title_full_unstemmed | Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging |
| title_short | Design and Fabrication of a Four-Dimentional Respiratory Phantom for Studying Tumor Movement in Radiotherapy with Magnetic Resonance Imaging |
| title_sort | design and fabrication of a four dimentional respiratory phantom for studying tumor movement in radiotherapy with magnetic resonance imaging |
| topic | Moving phantom Magnetic resonance imaging Radiotherapy Lung |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/4753 |
| work_keys_str_mv | AT zahraakmali designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging AT daryoushshahbazigahrouei designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging AT mohammadaminmoslehshirazi designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging AT miladbaradaranghahfarokhi designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging AT naderfallahian designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging AT sadeghsherkat designandfabricationofafourdimentionalrespiratoryphantomforstudyingtumormovementinradiotherapywithmagneticresonanceimaging |