Genetic predictors of obesity development
The most common reasons that cause obesity are eating disorders (overeating), genetic predisposition, sedentary lifestyle (lack of exercise), disorders of the endocrine system, and environmental factors. There is evidence of an obvious relationship of high consumption of sugary drinks and weight gai...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2016-07-01
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| Series: | Ожирение и метаболизм |
| Subjects: | |
| Online Access: | https://www.omet-endojournals.ru/jour/article/view/7854 |
| _version_ | 1797204600272453632 |
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| author | Svetlana V. Borodina Kamila M. Gapparova Zainudin M. Zainudiniv Olga N. Grigorian |
| author_facet | Svetlana V. Borodina Kamila M. Gapparova Zainudin M. Zainudiniv Olga N. Grigorian |
| author_sort | Svetlana V. Borodina |
| collection | DOAJ |
| description | The most common reasons that cause obesity are eating disorders (overeating), genetic predisposition, sedentary lifestyle (lack of exercise), disorders of the endocrine system, and environmental factors. There is evidence of an obvious relationship of high consumption of sugary drinks and weight gain. Since 1990, there has been considerable growth in the number of obese people in the first place associated with the promotion of soft drinks. According to a study in Finnish diabetes prevention average physical activity and change of diet (1200-1800 kcal) of total fat intake with less than 30% saturated fat, including less than 10%, leading to long-term loss of excess weight (within 4 years). Many studies have demonstrated the impossibility of a single template approach to the determination of optimal diets for patients with overweight and obesity which has been shown in various studies on gene polymorphisms are associated with obesity, and their interaction. This article provides an overview of current data on the genetics of obesity covering the main provisions of the study of candidate genes, such as PPARG, FABP2, ADRB 2, ADRB3. The role nutrigenetics in the creation of individual programs of weight control and weight loss. But the question of the direct role of genetic factors in the development of obesity remains controversial, since one can not ignore the impact of environmental factors, such as lifestyle, diet, physical activity, stress, and harmful habits. To understand the mechanism of the relationship between genetic factors, environmental factors, and obesity, one needs to carry out research not only on the population level, but also in certain groups of people (ethnic, racial, age). |
| first_indexed | 2024-03-08T09:13:09Z |
| format | Article |
| id | doaj.art-56e6a61e4e644107b1c1ab2da933d99f |
| institution | Directory Open Access Journal |
| issn | 2071-8713 2306-5524 |
| language | English |
| last_indexed | 2024-04-24T08:37:48Z |
| publishDate | 2016-07-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Ожирение и метаболизм |
| spelling | doaj.art-56e6a61e4e644107b1c1ab2da933d99f2024-04-16T16:16:10ZengEndocrinology Research CentreОжирение и метаболизм2071-87132306-55242016-07-0113271310.14341/omet201627-137388Genetic predictors of obesity developmentSvetlana V. Borodina0Kamila M. Gapparova1Zainudin M. Zainudiniv2Olga N. Grigorian3Research Institute of NutritionResearch Institute of NutritionResearch Institute of NutritionResearch Institute of NutritionThe most common reasons that cause obesity are eating disorders (overeating), genetic predisposition, sedentary lifestyle (lack of exercise), disorders of the endocrine system, and environmental factors. There is evidence of an obvious relationship of high consumption of sugary drinks and weight gain. Since 1990, there has been considerable growth in the number of obese people in the first place associated with the promotion of soft drinks. According to a study in Finnish diabetes prevention average physical activity and change of diet (1200-1800 kcal) of total fat intake with less than 30% saturated fat, including less than 10%, leading to long-term loss of excess weight (within 4 years). Many studies have demonstrated the impossibility of a single template approach to the determination of optimal diets for patients with overweight and obesity which has been shown in various studies on gene polymorphisms are associated with obesity, and their interaction. This article provides an overview of current data on the genetics of obesity covering the main provisions of the study of candidate genes, such as PPARG, FABP2, ADRB 2, ADRB3. The role nutrigenetics in the creation of individual programs of weight control and weight loss. But the question of the direct role of genetic factors in the development of obesity remains controversial, since one can not ignore the impact of environmental factors, such as lifestyle, diet, physical activity, stress, and harmful habits. To understand the mechanism of the relationship between genetic factors, environmental factors, and obesity, one needs to carry out research not only on the population level, but also in certain groups of people (ethnic, racial, age).https://www.omet-endojournals.ru/jour/article/view/7854obesitygenesdiet |
| spellingShingle | Svetlana V. Borodina Kamila M. Gapparova Zainudin M. Zainudiniv Olga N. Grigorian Genetic predictors of obesity development Ожирение и метаболизм obesity genes diet |
| title | Genetic predictors of obesity development |
| title_full | Genetic predictors of obesity development |
| title_fullStr | Genetic predictors of obesity development |
| title_full_unstemmed | Genetic predictors of obesity development |
| title_short | Genetic predictors of obesity development |
| title_sort | genetic predictors of obesity development |
| topic | obesity genes diet |
| url | https://www.omet-endojournals.ru/jour/article/view/7854 |
| work_keys_str_mv | AT svetlanavborodina geneticpredictorsofobesitydevelopment AT kamilamgapparova geneticpredictorsofobesitydevelopment AT zainudinmzainudiniv geneticpredictorsofobesitydevelopment AT olgangrigorian geneticpredictorsofobesitydevelopment |