Inferring the Association between the Risk of COVID-19 Case Fatality and N501Y Substitution in SARS-CoV-2

Inferring the Association between the Risk of COVID-19 Case Fatality and N501Y Substitution in SARS-CoV-2

As COVID-19 is posing a serious threat to global health, the emerging mutation in SARS-CoV-2 genomes, for example, N501Y substitution, is one of the major challenges against control of the pandemic. Characterizing the relationship between mutation activities and the risk of severe clinical outcomes...

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Bibliographic Details
Main Authors: Shi Zhao, Jingzhi Lou, Marc K. C. Chong, Lirong Cao, Hong Zheng, Zigui Chen, Renee W. Y. Chan, Benny C. Y. Zee, Paul K. S. Chan, Maggie H. Wang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
COVID-19
SARS-CoV-2
N501Y substitution
B.1.1.7 lineage
case fatality
statistical modelling
Online Access:https://www.mdpi.com/1999-4915/13/4/638

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