Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria

Aim. The study considers the influence of sensitive test-cultures on antagonistic activity and production antimicrobial factors by indigenous and probiotic microorganisms. Material. The original method has been used. It is based on determination of survival of sensitive test-culture under the action...

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Main Author: Semenov А.V.
Format: Article
Language:Russian
Published: Saratov State Medical University 2011-06-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201102_441-445.pdf
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author Semenov А.V.
author_facet Semenov А.V.
author_sort Semenov А.V.
collection DOAJ
description Aim. The study considers the influence of sensitive test-cultures on antagonistic activity and production antimicrobial factors by indigenous and probiotic microorganisms. Material. The original method has been used. It is based on determination of survival of sensitive test-culture under the action of cultural liquids of antagonist processed by metabolites and peptidoglycan of sensitive culture. Resalts. The important role of sensitive test-culture in manifestation of the antagonism active microorganisms has been proved. Received data have proved that antagonistic bacterial activity is a result of cross-species interaction between active and sensitive cultures. The effectors are antimicrobial factors and their regulators. The ability of bacterial peptidoglycan to regulate the cross-species interaction between prokaryotes has been firstly shown. Conclusion. The article concludes that the investigation has revealed new mechanisms of colonization resistance of biotope. It has opened prospects of development of principal new probiotic, prebiotic, sinbiotic, biologically active additive and functional products on the basis of microbial stimulators of bacterial antagonism
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spelling doaj.art-56eab59eea0f4a949b9d65b4ca65ae002022-12-21T22:07:02ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182011-06-0172441445Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteriaSemenov А.V.Aim. The study considers the influence of sensitive test-cultures on antagonistic activity and production antimicrobial factors by indigenous and probiotic microorganisms. Material. The original method has been used. It is based on determination of survival of sensitive test-culture under the action of cultural liquids of antagonist processed by metabolites and peptidoglycan of sensitive culture. Resalts. The important role of sensitive test-culture in manifestation of the antagonism active microorganisms has been proved. Received data have proved that antagonistic bacterial activity is a result of cross-species interaction between active and sensitive cultures. The effectors are antimicrobial factors and their regulators. The ability of bacterial peptidoglycan to regulate the cross-species interaction between prokaryotes has been firstly shown. Conclusion. The article concludes that the investigation has revealed new mechanisms of colonization resistance of biotope. It has opened prospects of development of principal new probiotic, prebiotic, sinbiotic, biologically active additive and functional products on the basis of microbial stimulators of bacterial antagonismhttp://www.ssmj.ru/system/files/201102_441-445.pdfantagonismassociative microorganismscross-speciespeptidoglycanprebiotic
spellingShingle Semenov А.V.
Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
Саратовский научно-медицинский журнал
antagonism
associative microorganisms
cross-species
peptidoglycan
prebiotic
title Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
title_full Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
title_fullStr Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
title_full_unstemmed Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
title_short Role of sensitive test-cultures in manifestation of antagonism by human symbiotic bacteria
title_sort role of sensitive test cultures in manifestation of antagonism by human symbiotic bacteria
topic antagonism
associative microorganisms
cross-species
peptidoglycan
prebiotic
url http://www.ssmj.ru/system/files/201102_441-445.pdf
work_keys_str_mv AT semenovav roleofsensitivetestculturesinmanifestationofantagonismbyhumansymbioticbacteria