PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA
The ability to metastasize is considered to be one of the key features of malignant tumors. However, the literature describes the possibility of dissemination of histologically verified benign tumors – uterine leiomyoma. Diagnosis of metastatic leiomyoma is a challenging task for the doctor, due to...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2017-03-01
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| Series: | Сибирский онкологический журнал |
| Subjects: | |
| Online Access: | https://www.siboncoj.ru/jour/article/view/499 |
| _version_ | 1826563794319441920 |
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| author | A. S. Subbotin A. V. Vazhenin N. G. Afanasyeva |
| author_facet | A. S. Subbotin A. V. Vazhenin N. G. Afanasyeva |
| author_sort | A. S. Subbotin |
| collection | DOAJ |
| description | The ability to metastasize is considered to be one of the key features of malignant tumors. However, the literature describes the possibility of dissemination of histologically verified benign tumors – uterine leiomyoma. Diagnosis of metastatic leiomyoma is a challenging task for the doctor, due to the extreme rarity of this disease, at the same time revealing the purity of the process is determining the further tactics of treatment, significantly different from the treatment of malignancies. Case report. We presented a rare case of dissemination of benign tumors – leiomyomas. The female patient of 72 years old had signs of typical malignant tumors of the ovaries, such as nodules of the abdominal cavity, ascites and metastases in the body of the lumbar vertebra, increased level of CA-125. PET-CT revealed increased FDG uptake in soft-tissue neoplasm that destruct the body of the lumbar vertebrae and the nodules in the abdominal cavity with increased metabolic activity, typical for malignant tumors. However, histological examination with immunohistochemical verification confirmed the presence of dissemination of benign tumors. Conclusion. The presence of signs, typical for the malignant tumor, such as the presence of distant metastases of various localizations, a high level of CA-125 tumor marker, increased metabolic activity on PET scan in rare cases, may occur with benign tumors. Therefore, diagnosis of tumors should always be integrated, with the obligatory account all available clinical, laboratory and instrumental data. |
| first_indexed | 2024-04-10T01:53:15Z |
| format | Article |
| id | doaj.art-56edb487c84641c98f393d12099c8f73 |
| institution | Directory Open Access Journal |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| last_indexed | 2025-03-14T10:09:37Z |
| publishDate | 2017-03-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj.art-56edb487c84641c98f393d12099c8f732025-03-02T11:16:08ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682017-03-0116110410810.21294/1814-4861-2017-16-1-104-108425PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMAA. S. Subbotin0A. V. Vazhenin1N. G. Afanasyeva2Chelyabinsk State Regional Oncological Hospital, ChelyabinskChelyabinsk State Regional Oncological Hospital, ChelyabinskChelyabinsk State Regional Oncological Hospital, ChelyabinskThe ability to metastasize is considered to be one of the key features of malignant tumors. However, the literature describes the possibility of dissemination of histologically verified benign tumors – uterine leiomyoma. Diagnosis of metastatic leiomyoma is a challenging task for the doctor, due to the extreme rarity of this disease, at the same time revealing the purity of the process is determining the further tactics of treatment, significantly different from the treatment of malignancies. Case report. We presented a rare case of dissemination of benign tumors – leiomyomas. The female patient of 72 years old had signs of typical malignant tumors of the ovaries, such as nodules of the abdominal cavity, ascites and metastases in the body of the lumbar vertebra, increased level of CA-125. PET-CT revealed increased FDG uptake in soft-tissue neoplasm that destruct the body of the lumbar vertebrae and the nodules in the abdominal cavity with increased metabolic activity, typical for malignant tumors. However, histological examination with immunohistochemical verification confirmed the presence of dissemination of benign tumors. Conclusion. The presence of signs, typical for the malignant tumor, such as the presence of distant metastases of various localizations, a high level of CA-125 tumor marker, increased metabolic activity on PET scan in rare cases, may occur with benign tumors. Therefore, diagnosis of tumors should always be integrated, with the obligatory account all available clinical, laboratory and instrumental data.https://www.siboncoj.ru/jour/article/view/499leiomyomaleiomyomatosis peritonealis disseminatepet-ct |
| spellingShingle | A. S. Subbotin A. V. Vazhenin N. G. Afanasyeva PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA Сибирский онкологический журнал leiomyoma leiomyomatosis peritonealis disseminate pet-ct |
| title | PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA |
| title_full | PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA |
| title_fullStr | PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA |
| title_full_unstemmed | PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA |
| title_short | PET-CT FINDING OF BENIGN METASTASIZING LEIOMYOMA |
| title_sort | pet ct finding of benign metastasizing leiomyoma |
| topic | leiomyoma leiomyomatosis peritonealis disseminate pet-ct |
| url | https://www.siboncoj.ru/jour/article/view/499 |
| work_keys_str_mv | AT assubbotin petctfindingofbenignmetastasizingleiomyoma AT avvazhenin petctfindingofbenignmetastasizingleiomyoma AT ngafanasyeva petctfindingofbenignmetastasizingleiomyoma |