Creation of a non-Western humanized gnotobiotic mouse model through the transplantation of rural African fecal microbiota

Creation of a non-Western humanized gnotobiotic mouse model through the transplantation of rural African fecal microbiota

ABSTRACT Gut microbiota are increasingly being recognized as a contributing factor in the etiology of numerous diseases and as a potential determinant in the immune response to various treatments. Recent work has suggested that the suboptimal immunogenic response to vaccination in low- and middle-in...

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Main Authors: Kristin M. Van Den Ham, Morgan R. Little, Olivia J. Bednarski, Elizabeth M. Fusco, Rabindra K. Mandal, Riten Mitra, Shanping Li, Safiatou Doumbo, Didier Doumtabe, Kassoum Kayentao, Aissata Ongoiba, Boubacar Traore, Peter D. Crompton, Nathan W. Schmidt
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
germ free mice
intestinal colonization
non-Western stool
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01554-23

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