Enteroaggregative <italic toggle="yes">Escherichia coli</italic> Adherence Fimbriae Drive Inflammatory Cell Recruitment via Interactions with Epithelial MUC1

Enteroaggregative <italic toggle="yes">Escherichia coli</italic> Adherence Fimbriae Drive Inflammatory Cell Recruitment via Interactions with Epithelial MUC1

ABSTRACT Enteroaggregative Escherichia coli (EAEC) causes diarrhea and intestinal inflammation worldwide. EAEC strains are characterized by the presence of aggregative adherence fimbriae (AAF), which play a key role in pathogenesis by mediating attachment to the intestinal mucosa and by triggering h...

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Bibliographic Details
Main Authors: Erik J. Boll, Jorge Ayala-Lujan, Rose L. Szabady, Christopher Louissaint, Rachel Z. Smith, Karen A. Krogfelt, James P. Nataro, Fernando Ruiz-Perez, Beth A. McCormick
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
Escherichia coli
fimbriae
inflammation
mucin
Online Access:https://journals.asm.org/doi/10.1128/mBio.00717-17

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