Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder

ABSTRACTBackground: Knowledge of treatment predictors and moderators is important for improving the effectiveness of treatment for PTSD due to childhood abuse.Objective: The first aim of this study was to test the potential predictive value of variables commonly associated with PTSD resulting from a...

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Main Authors: Noortje I. van Vliet, Rafaele J. C. Huntjens, Maarten K. van Dijk, Mark Huisman, Nathan Bachrach, Marie-Louise Meewisse, Sietske van Haren, Ad de Jongh
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:European Journal of Psychotraumatology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/20008066.2023.2300589
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author Noortje I. van Vliet
Rafaele J. C. Huntjens
Maarten K. van Dijk
Mark Huisman
Nathan Bachrach
Marie-Louise Meewisse
Sietske van Haren
Ad de Jongh
author_facet Noortje I. van Vliet
Rafaele J. C. Huntjens
Maarten K. van Dijk
Mark Huisman
Nathan Bachrach
Marie-Louise Meewisse
Sietske van Haren
Ad de Jongh
author_sort Noortje I. van Vliet
collection DOAJ
description ABSTRACTBackground: Knowledge of treatment predictors and moderators is important for improving the effectiveness of treatment for PTSD due to childhood abuse.Objective: The first aim of this study was to test the potential predictive value of variables commonly associated with PTSD resulting from a history of repeated childhood abuse, in relation to treatment outcomes. The second aim was to examine if complex PTSD symptoms act as potential moderators between treatment conditions and outcomes.Method: Data were obtained from a randomized controlled trial comparing a phase-based treatment (Skills Training in Affect and Interpersonal Regulation [STAIR] followed by Eye Movement Desensitization and Reprocessing [EMDR] therapy; n = 57) with a direct trauma-focused treatment (EMDR therapy only; n = 64) in people with PTSD due to childhood abuse. The possible predictive effects of the presence of borderline personality disorder, dissociative symptoms, and suicidal and self-injurious behaviours were examined. In addition, it was determined whether symptoms of emotion regulation difficulties, self-esteem, and interpersonal problems moderated the relation between the treatment condition and PTSD post-treatment, corrected for pre-treatment PTSD severity.Results: Pre-treatment PTSD severity proved to be a significant predictor of less profitable PTSD treatment outcomes. The same was true for the severity of dissociative symptoms, but only post-treatment, and not when corrected for false positives. Complex PTSD symptoms did not moderate the relationship between the treatment conditions and PTSD treatment outcomes.Conclusions: The current findings suggest that regardless of the common comorbid symptoms studied, immediate trauma-focused treatment is a safe and effective option for individuals with childhood-related PTSD. However, individuals experiencing severe symptoms of PTSD may benefit from additional treatment sessions or the addition of other evidence-based PTSD treatment approaches. The predictive influence of dissociative sequelae needs further research.The study design was registered in The Dutch trial register (https://www.trialregister.nl/trialreg/admin/rctview.asp?TC = 5991) NTR5991 and was approved by the medical ethics committee of Twente NL 56641.044.16 CCMO.
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spelling doaj.art-56f6790cb2f3448e96b8cd90870600212024-01-17T10:47:48ZengTaylor & Francis GroupEuropean Journal of Psychotraumatology2000-80662024-12-0115110.1080/20008066.2023.2300589Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorderNoortje I. van Vliet0Rafaele J. C. Huntjens1Maarten K. van Dijk2Mark Huisman3Nathan Bachrach4Marie-Louise Meewisse5Sietske van Haren6Ad de Jongh7Dimence Mental Health Group, Deventer, the NetherlandsDepartment of Experimental Psychotherapy and Psychopathology, University of Groningen, Groningen, the NetherlandsDimence Mental Health Group, Deventer, the NetherlandsDepartment of Sociology, University of Groningen, Groningen, the NetherlandsGGZ Oost Brabant, Helmond, the NetherlandsAbate Center of Expertise in Anxiety and Trauma, Grootebroek, the NetherlandsBuurtzorgT, Deventer, the NetherlandsDepartment of Oral public health, Academic Centre of Dentistry (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, NetherlandsABSTRACTBackground: Knowledge of treatment predictors and moderators is important for improving the effectiveness of treatment for PTSD due to childhood abuse.Objective: The first aim of this study was to test the potential predictive value of variables commonly associated with PTSD resulting from a history of repeated childhood abuse, in relation to treatment outcomes. The second aim was to examine if complex PTSD symptoms act as potential moderators between treatment conditions and outcomes.Method: Data were obtained from a randomized controlled trial comparing a phase-based treatment (Skills Training in Affect and Interpersonal Regulation [STAIR] followed by Eye Movement Desensitization and Reprocessing [EMDR] therapy; n = 57) with a direct trauma-focused treatment (EMDR therapy only; n = 64) in people with PTSD due to childhood abuse. The possible predictive effects of the presence of borderline personality disorder, dissociative symptoms, and suicidal and self-injurious behaviours were examined. In addition, it was determined whether symptoms of emotion regulation difficulties, self-esteem, and interpersonal problems moderated the relation between the treatment condition and PTSD post-treatment, corrected for pre-treatment PTSD severity.Results: Pre-treatment PTSD severity proved to be a significant predictor of less profitable PTSD treatment outcomes. The same was true for the severity of dissociative symptoms, but only post-treatment, and not when corrected for false positives. Complex PTSD symptoms did not moderate the relationship between the treatment conditions and PTSD treatment outcomes.Conclusions: The current findings suggest that regardless of the common comorbid symptoms studied, immediate trauma-focused treatment is a safe and effective option for individuals with childhood-related PTSD. However, individuals experiencing severe symptoms of PTSD may benefit from additional treatment sessions or the addition of other evidence-based PTSD treatment approaches. The predictive influence of dissociative sequelae needs further research.The study design was registered in The Dutch trial register (https://www.trialregister.nl/trialreg/admin/rctview.asp?TC = 5991) NTR5991 and was approved by the medical ethics committee of Twente NL 56641.044.16 CCMO.https://www.tandfonline.com/doi/10.1080/20008066.2023.2300589PTSDchildhood abusepredictorsmoderatorstreatmentTEPT
spellingShingle Noortje I. van Vliet
Rafaele J. C. Huntjens
Maarten K. van Dijk
Mark Huisman
Nathan Bachrach
Marie-Louise Meewisse
Sietske van Haren
Ad de Jongh
Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
European Journal of Psychotraumatology
PTSD
childhood abuse
predictors
moderators
treatment
TEPT
title Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
title_full Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
title_fullStr Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
title_full_unstemmed Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
title_short Predictors and moderators of treatment outcomes in phase-based treatment and trauma-focused treatments in patients with childhood abuse-related post-traumatic stress disorder
title_sort predictors and moderators of treatment outcomes in phase based treatment and trauma focused treatments in patients with childhood abuse related post traumatic stress disorder
topic PTSD
childhood abuse
predictors
moderators
treatment
TEPT
url https://www.tandfonline.com/doi/10.1080/20008066.2023.2300589
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