Effects of Fatty Acid Salts against Trichophyton Violaceum

Trichophyton violaceum is an anthropophilic fungus. Dermatophytosis (Tinea) is fungal infection that can infect the scalp, glabrous skin, and nails. In general, Tinea can be spread by skin-to-skin contact or bathroom or floor materials. The treatments of Tinea need antifungal medication and good hyg...

Full description

Bibliographic Details
Main Authors: Era Mariko, Kawahara Takayoshi, Kanyama Takahide, Morita Hiroshi
Format: Article
Language:English
Published: EDP Sciences 2016-01-01
Series:MATEC Web of Conferences
Online Access:http://dx.doi.org/10.1051/matecconf/20166003004
_version_ 1818621304573526016
author Era Mariko
Kawahara Takayoshi
Kanyama Takahide
Morita Hiroshi
author_facet Era Mariko
Kawahara Takayoshi
Kanyama Takahide
Morita Hiroshi
author_sort Era Mariko
collection DOAJ
description Trichophyton violaceum is an anthropophilic fungus. Dermatophytosis (Tinea) is fungal infection that can infect the scalp, glabrous skin, and nails. In general, Tinea can be spread by skin-to-skin contact or bathroom or floor materials. The treatments of Tinea need antifungal medication and good hygiene environment. The effective antifungal medication and infection prevention, and the creation of antifungal medication with high safety are required. In this study was focused on the antifungal effect of fatty acids potassium salts. The antifungal activity of nine fatty acid salts (butyrate, caproate, caprylate, caprate, laurate, myristate, oleate, linoleate, and linolenate) was tested on the spores of Trichophyton violaceum NBRC 31064. The results show that C6K, C8K, C10K, C12K, C18:2K, C18:3K was the most inhibit 4-log unit (99.99 %) of the fatty acids potassium incubated time for 10 min. It was observed that C12K and C18:3K was most high antifungal activity MIC. Commercially soap was lowest antifungal activity. This is because of the oleic acid is a major component of soap. Although further investigation is necessary to make clear antifungal mechanisms, our results suggest that fatty acid potassium will use to the development of a coating agent such as furniture.
first_indexed 2024-12-16T18:07:09Z
format Article
id doaj.art-56f884d84b764ea785d06c7f9c4ab414
institution Directory Open Access Journal
issn 2261-236X
language English
last_indexed 2024-12-16T18:07:09Z
publishDate 2016-01-01
publisher EDP Sciences
record_format Article
series MATEC Web of Conferences
spelling doaj.art-56f884d84b764ea785d06c7f9c4ab4142022-12-21T22:21:53ZengEDP SciencesMATEC Web of Conferences2261-236X2016-01-01600300410.1051/matecconf/20166003004matecconf_iccbs2016_03004Effects of Fatty Acid Salts against Trichophyton ViolaceumEra Mariko0Kawahara Takayoshi1Kanyama Takahide2Morita Hiroshi3Graduate school of Environmental Engineering, The University of KitakyusyuShabondama Soap Co., LtdShabondama Soap Co., LtdFaculty of Environmental Engineering, The University of KitakyusyuTrichophyton violaceum is an anthropophilic fungus. Dermatophytosis (Tinea) is fungal infection that can infect the scalp, glabrous skin, and nails. In general, Tinea can be spread by skin-to-skin contact or bathroom or floor materials. The treatments of Tinea need antifungal medication and good hygiene environment. The effective antifungal medication and infection prevention, and the creation of antifungal medication with high safety are required. In this study was focused on the antifungal effect of fatty acids potassium salts. The antifungal activity of nine fatty acid salts (butyrate, caproate, caprylate, caprate, laurate, myristate, oleate, linoleate, and linolenate) was tested on the spores of Trichophyton violaceum NBRC 31064. The results show that C6K, C8K, C10K, C12K, C18:2K, C18:3K was the most inhibit 4-log unit (99.99 %) of the fatty acids potassium incubated time for 10 min. It was observed that C12K and C18:3K was most high antifungal activity MIC. Commercially soap was lowest antifungal activity. This is because of the oleic acid is a major component of soap. Although further investigation is necessary to make clear antifungal mechanisms, our results suggest that fatty acid potassium will use to the development of a coating agent such as furniture.http://dx.doi.org/10.1051/matecconf/20166003004
spellingShingle Era Mariko
Kawahara Takayoshi
Kanyama Takahide
Morita Hiroshi
Effects of Fatty Acid Salts against Trichophyton Violaceum
MATEC Web of Conferences
title Effects of Fatty Acid Salts against Trichophyton Violaceum
title_full Effects of Fatty Acid Salts against Trichophyton Violaceum
title_fullStr Effects of Fatty Acid Salts against Trichophyton Violaceum
title_full_unstemmed Effects of Fatty Acid Salts against Trichophyton Violaceum
title_short Effects of Fatty Acid Salts against Trichophyton Violaceum
title_sort effects of fatty acid salts against trichophyton violaceum
url http://dx.doi.org/10.1051/matecconf/20166003004
work_keys_str_mv AT eramariko effectsoffattyacidsaltsagainsttrichophytonviolaceum
AT kawaharatakayoshi effectsoffattyacidsaltsagainsttrichophytonviolaceum
AT kanyamatakahide effectsoffattyacidsaltsagainsttrichophytonviolaceum
AT moritahiroshi effectsoffattyacidsaltsagainsttrichophytonviolaceum