The TNFSF Members APRIL and BAFF and Their Receptors TACI, BCMA, and BAFFR in Oncology, With a Special Focus in Breast Cancer

The TNFSF Members APRIL and BAFF and Their Receptors TACI, BCMA, and BAFFR in Oncology, With a Special Focus in Breast Cancer

Tumor necrosis factor (TNF) superfamily consists of 19 ligands and 29 receptors and is related to multiple cellular events from proliferation and differentiation to apoptosis and tumor reduction. In this review, we overview the whole system, and we focus on A proliferation-inducing ligand (APRIL, TN...

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Bibliographic Details
Main Authors: Marilena Kampa, George Notas, Efstathios N. Stathopoulos, Andreas Tsapis, Elias Castanas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
APRIL (TNFSF13)
BAFF (TNFSF13B)
BCMA (TNFRSF17)
TACI (TNFRSF13B)
BAFFR (TNFRSF13C)
breast cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00827/full

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