Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake

Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake

Conjugation of small molecules such as lipids or receptor ligands to anti-cancer drugs has been used to improve their pharmacological properties. In this work, we studied the biological effects of several small-molecule enhancers into a short oligonucleotide made of five floxuridine units. Specifica...

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Bibliographic Details
Main Authors:	Anna Aviñó, Anna Clua, Maria José Bleda, Ramon Eritja, Carme Fàbrega
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	International Journal of Molecular Sciences
Subjects:	5-fluoro-2′-deoxyuridine delivery enhancers cholesterol palmitic acid folic acid GalNAc
Online Access:	https://www.mdpi.com/1422-0067/22/11/5678

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