BdLT-Seq as a barcode decay-based method to unravel lineage-linked transcriptome plasticity

Cellular plasticity is a core biological process; however, observing diversity in non-genetic inheritance and the resulting phenotypic outputs, is challenging. Here the authors develop a non-genetically based tracing technology which can be used to reveal lineage-linked transcriptome plasticity.

Bibliographic Details
Main Authors: Yelyzaveta Shlyakhtina, Bianca Bloechl, Maximiliano M. Portal
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36744-1
Description
Summary:Cellular plasticity is a core biological process; however, observing diversity in non-genetic inheritance and the resulting phenotypic outputs, is challenging. Here the authors develop a non-genetically based tracing technology which can be used to reveal lineage-linked transcriptome plasticity.
ISSN:2041-1723