Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application

Although vascular stents have been widely used in clinical practice, there is still a risk of in-stent restenosis after their implantation. Combining conventional vascular stents with liquid metal-based electrodes with impedance detection, irreversible electroporation, and blood pressure detection p...

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Main Authors: Xilong Zhang, Lei Li, Zhongshan Deng
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/13/8/795
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author Xilong Zhang
Lei Li
Zhongshan Deng
author_facet Xilong Zhang
Lei Li
Zhongshan Deng
author_sort Xilong Zhang
collection DOAJ
description Although vascular stents have been widely used in clinical practice, there is still a risk of in-stent restenosis after their implantation. Combining conventional vascular stents with liquid metal-based electrodes with impedance detection, irreversible electroporation, and blood pressure detection provides a new direction to completely solve the restenosis problem. Compared with conventional rigid electrodes, liquid metal-based electrodes combine high conductivity and stretchability, and are more compliant with the implantation process of vascular stents and remain in the vasculature for a long period of time. This perspective reviews the types and development of conventional vascular stents and proposes a novel stent that integrates liquid metal-based electrodes on conventional vascular stents. This vascular stent has three major functions of prediction, detection and treatment, and is expected to be a new generation of cardiovascular implant with intelligent sensing and real-time monitoring.
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spelling doaj.art-570278dfe9b4440fbe1773bedbdc22f82023-11-19T00:25:20ZengMDPI AGBiosensors2079-63742023-08-0113879510.3390/bios13080795Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential ApplicationXilong Zhang0Lei Li1Zhongshan Deng2Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaKey Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaKey Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaAlthough vascular stents have been widely used in clinical practice, there is still a risk of in-stent restenosis after their implantation. Combining conventional vascular stents with liquid metal-based electrodes with impedance detection, irreversible electroporation, and blood pressure detection provides a new direction to completely solve the restenosis problem. Compared with conventional rigid electrodes, liquid metal-based electrodes combine high conductivity and stretchability, and are more compliant with the implantation process of vascular stents and remain in the vasculature for a long period of time. This perspective reviews the types and development of conventional vascular stents and proposes a novel stent that integrates liquid metal-based electrodes on conventional vascular stents. This vascular stent has three major functions of prediction, detection and treatment, and is expected to be a new generation of cardiovascular implant with intelligent sensing and real-time monitoring.https://www.mdpi.com/2079-6374/13/8/795vascular stentliquid metalin-stent restenosisirreversible electroporationbiosensor
spellingShingle Xilong Zhang
Lei Li
Zhongshan Deng
Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
Biosensors
vascular stent
liquid metal
in-stent restenosis
irreversible electroporation
biosensor
title Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
title_full Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
title_fullStr Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
title_full_unstemmed Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
title_short Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application
title_sort liquid metal based flexible bioelectrodes for management of in stent restenosis potential application
topic vascular stent
liquid metal
in-stent restenosis
irreversible electroporation
biosensor
url https://www.mdpi.com/2079-6374/13/8/795
work_keys_str_mv AT xilongzhang liquidmetalbasedflexiblebioelectrodesformanagementofinstentrestenosispotentialapplication
AT leili liquidmetalbasedflexiblebioelectrodesformanagementofinstentrestenosispotentialapplication
AT zhongshandeng liquidmetalbasedflexiblebioelectrodesformanagementofinstentrestenosispotentialapplication